Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21801148 | 1.00 | CYSLTR1 (0.45) | CYSLTR1ABCB1BCHECNR2MAOB | |
| SCHEMBL30744089 | 1.00 | CYSLTR1 (0.45) | CYSLTR1ABCB1BCHECNR2MAOB | |
| SCHEMBL21801141 | 1.00 | CYSLTR1 (0.45) | CYSLTR1ABCB1BCHECNR2MAOB | |
| SCHEMBL21865983 | 1.00 | CYSLTR1 (0.45) | CYSLTR1ABCB1BCHECNR2MAOB | |
| SCHEMBL21801143 | 1.00 | CYSLTR1 (0.45) | CYSLTR1ABCB1BCHECNR2MAOB | |
| SCHEMBL30744083 | 1.00 | CYSLTR1 (0.45) | CYSLTR1ABCB1BCHECNR2MAOB | |
| SCHEMBL21801189 | 0.89 | SIGMAR1 (0.45) | CYSLTR1ABCB1BCHECNR2MAOB | |
| SCHEMBL30744100 | 0.89 | SIGMAR1 (0.45) | CYSLTR1ABCB1BCHECNR2MAOB | |
| SCHEMBL26672824 | 0.89 | SIGMAR1 (0.45) | CYSLTR1ABCB1BCHECNR2MAOB | |
| SCHEMBL21801083 | 0.88 | CYSLTR1 (0.45) | CYSLTR1ABCB1BCHECNR2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020052774-A1 | FLAVONE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS DISEASE | F. HOFFMANN-LA ROCHE AG (CH) | 2020-03-19 | — | — | WO | disclosed |