⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29055224 | 1.00 | — | — | |
| SCHEMBL1277270 | 1.00 | — | — | |
| SCHEMBL9126848 | 0.82 | — | — | |
| SCHEMBL2229643 | 0.80 | ALDH1A1 (0.39) | — | |
| SCHEMBL6044981 | 0.80 | GRIK1 (0.35) | — | |
| SCHEMBL11767085 | 0.80 | GRIK1 (0.38) | — | |
| SCHEMBL4423141 | 0.79 | — | — | |
| SCHEMBL16440995 | 0.79 | — | — | |
| SCHEMBL5921557 | 0.79 | — | — | |
| SCHEMBL1277052 | 0.78 | NPSR1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2705390-A1 | MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME | Johnson & Johnson Vision Care Inc. (US) | 2014-03-12 | — | — | EP | disclosed |
| WO-2012151135-A1 | MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2012-11-08 | — | — | WO | disclosed |
| EP-2342588-A1 | IONIC SILICONE HYDROGELS HAVING IMPROVED HYDROLYTIC STABILITY | Johnson & Johnson Vision Care, Inc. (US) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010039653-A1 | IONIC SILICONE HYDROGELS HAVING IMPROVED HYDROLYTIC STABILITY | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2010-04-08 | — | — | WO | disclosed |