Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 6/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13870905 | 0.79 | CYP1A2 (0.41) | LMNACYP1A2ARMAPTMEN1 | |
| SCHEMBL12319823 | 0.78 | AR (0.57) | LMNACYP1A2ARMAPTMEN1 | |
| SCHEMBL4434489 | 0.76 | RAB9A (0.40) | LMNACYP1A2TRPA1PTGS1CACNA1C | |
| SCHEMBL13870934 | 0.74 | PDGFRB (0.43) | CYP1A2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL13989400 | 0.74 | CYP1A2 (0.52) | CYP1A2ARESR1MAPTKMT2A | |
| SCHEMBL30273432 | 0.72 | ESR1 (0.54) | LMNACYP1A2ARESR1MAPT | |
| SCHEMBL13989422 | 0.72 | ESR1 (0.54) | LMNACYP1A2ARESR1MAPT | |
| SCHEMBL13989405 | 0.72 | CYP1A2 (0.53) | LMNACYP1A2ARESR1MAPT | |
| SCHEMBL13870959 | 0.72 | KMT2A (0.43) | CYP1A2ESR1MAPTMEN1KMT2A | |
| SCHEMBL26675645 | 0.71 | DHODH (0.48) | LMNACYP1A2ARMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632921-A1 | ANCILLARY LIGANDS FOR ORGANOMETALLIC COMPLEXES | Universal Display Corporation (US) | 2020-04-08 | — | — | EP | disclosed |