SCHEMBL21886512

SCHEMBL21886512

CCCCCCCOC(CCCCCCCCCN)OCCCCCCC

nearest known ligand 0.52

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 9/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
ALDH1A1 P00352 1/20 0.52
TSHR P16473 1/20 0.52
EPHX1 P07099 1/20 0.52
TLR2 O60603 4/20 0.46
SMPD1 P17405 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6575132 0.94 DNM1 (0.48) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL3244710 0.94 DNM1 (0.53) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL4172517 0.94 DNM1 (0.53) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL21599287 0.94 DNM1 (0.53) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL3235752 0.94 DNM1 (0.53) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL6577275 0.94 DNM1 (0.48) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL3242905 0.94 DNM1 (0.53) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL6574288 0.92 DNM1 (0.44) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL18180586 0.89 DNM1 (0.50) DNM1TSHRSMPD1
SCHEMBL873033 0.89 DNM1 (0.50) DNM1TSHRSMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020072605-A1 IONIZABLE AMINE LIPIDS INTELLIA THERAPEUTICS, INC. (US) 2020-04-09 WO disclosed