SCHEMBL21886718

SCHEMBL21886718

O=C(OC[C@@H]1OC[C@H](OC(=O)c2ccccc2)[C@H]1OC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ BCHE P06276 6/20 0.49
▸ POLB P06746 2/20 0.46
▸ MEN1 O00255 1/20 0.46
▸ USP2 O75604 1/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ PTPN1 P18031 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.43
▸ GAA P10253 1/20 0.42
▸ MAPK1 P28482 1/20 0.42
▸ NPSR1 Q6W5P4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16749107 1.00 BCHE (0.49) BCHEPOLBMEN1USP2KMT2A
SCHEMBL19944547 1.00 BCHE (0.49) BCHEPOLBMEN1USP2KMT2A
SCHEMBL28213216 1.00 BCHE (0.49) BCHEPOLBMEN1USP2KMT2A
SCHEMBL14208566 1.00 BCHE (0.49) BCHEPOLBMEN1USP2KMT2A
SCHEMBL14413573 1.00 BCHE (0.49) BCHEPOLBMEN1USP2KMT2A
SCHEMBL23348434 1.00 BCHE (0.49) BCHEPOLBMEN1USP2KMT2A
SCHEMBL22166492 0.96 BCHE (0.48) BCHEPOLBMEN1USP2KMT2A
SCHEMBL20713679 0.96 BCHE (0.48) BCHEPOLBMEN1USP2KMT2A
SCHEMBL21650368 0.96 BCHE (0.48) BCHEPOLBMEN1USP2KMT2A
SCHEMBL18654234 0.96 BCHE (0.48) BCHEPOLBMEN1USP2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159922-A1 MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF IONIS PHARMACEUTICALS, INC. (US) 2023-05-25 — — US disclosed
WO-2021030763-A1 MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF IONIS PHARMACEUTICALS, INC. (US) 2021-02-18 — — WO disclosed
WO-2020072991-A1 MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF IONIS PHARMACEUTICALS, INC. (US) 2020-04-09 — — WO disclosed
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