Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18654234 | 1.00 | BCHE (0.48) | BCHEMEN1USP2POLBKMT2A | |
| SCHEMBL21650368 | 1.00 | BCHE (0.48) | BCHEMEN1USP2POLBKMT2A | |
| SCHEMBL24379967 | 1.00 | BCHE (0.48) | BCHEMEN1USP2POLBKMT2A | |
| SCHEMBL22166492 | 1.00 | BCHE (0.48) | BCHEMEN1USP2POLBKMT2A | |
| SCHEMBL21886718 | 0.96 | BCHE (0.49) | BCHEMEN1USP2POLBKMT2A | |
| SCHEMBL14413573 | 0.96 | BCHE (0.49) | BCHEMEN1USP2POLBKMT2A | |
| SCHEMBL19944547 | 0.96 | BCHE (0.49) | BCHEMEN1USP2POLBKMT2A | |
| SCHEMBL23348434 | 0.96 | BCHE (0.49) | BCHEMEN1USP2POLBKMT2A | |
| SCHEMBL14208566 | 0.96 | BCHE (0.49) | BCHEMEN1USP2POLBKMT2A | |
| SCHEMBL16749107 | 0.96 | BCHE (0.49) | BCHEMEN1USP2POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230134986-A1 | GLUCOSE TRIPTOLIDE CONJUGATES AND USES THEREOF | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2023-05-04 | — | — | US | disclosed |
| US-20200297693-A1 | GLUCOSE CONJUGATES OF TRIPTOLIDE, ANALOGS AND USES THEREOF | THE JOHNS HOPKINS UNIVERSITY | 2020-09-24 | — | — | US | disclosed |
| US-10695319-B2 | Glucose conjugates of triptolide, analogs and uses thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2020-06-30 | — | — | US | disclosed |
| US-20190038596-A1 | GLUCOSE CONJUGATES OF TRIPTOLIDE, ANALOGS AND USES THEREOF | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2019-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190038596-A1 | GLUCOSE CONJUGATES OF TRIPTOLIDE, ANALOGS AND USES THEREOF | SLC2A8, SLC2A4, SLC2A1 | BCHE 2800/4885MEN1 725/4885USP2 1793/4885 |
| US-20200297693-A1 | GLUCOSE CONJUGATES OF TRIPTOLIDE, ANALOGS AND USES THEREOF | SLC2A8, SLC2A4, SLC2A1 | BCHE 2800/4885MEN1 725/4885USP2 1793/4885 |
| US-10695319-B2 | Glucose conjugates of triptolide, analogs and uses thereof | SLC2A8, SLC2A4, SLC2A1 | BCHE 2800/4885MEN1 725/4885USP2 1793/4885 |
| US-20230134986-A1 | GLUCOSE TRIPTOLIDE CONJUGATES AND USES THEREOF | SLC2A1, SLC2A9, GID4 | BCHE 4730/4885MEN1 3088/4885USP2 1955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.