Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | ELANE | P08246 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | S100A4 | P26447 | 3/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | CTH | P32929 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | BRCA1 | P38398 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 3/20 | 0.41 |
| ▸ | BLM | P54132 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11429902 | 1.00 | EGFR (0.51) | EGFRPIM1CYP1A2ELANEMEN1 | |
| SCHEMBL22873368 | 0.91 | EGFR (0.51) | EGFRPIM1CYP1A2ELANEMEN1 | |
| SCHEMBL11395596 | 0.91 | EGFR (0.51) | EGFRPIM1CYP1A2ELANEMEN1 | |
| SCHEMBL23022615 | 0.88 | EGFR (0.48) | EGFRPIM1ELANEMEN1KMT2A | |
| SCHEMBL21650333 | 0.88 | EGFR (0.48) | EGFRPIM1CYP1A2ELANEMEN1 | |
| SCHEMBL8171745 | 0.88 | EGFR (0.48) | EGFRPIM1ELANEMEN1KMT2A | |
| SCHEMBL13444092 | 0.88 | EGFR (0.48) | EGFRPIM1ELANEMEN1KMT2A | |
| SCHEMBL19789618 | 0.87 | EGFR (0.47) | EGFRPIM1ELANEMEN1KMT2A | |
| SCHEMBL16848014 | 0.87 | EGFR (0.47) | EGFRPIM1ELANEMEN1KMT2A | |
| SCHEMBL11402047 | 0.87 | CYP1A2 (0.48) | EGFRPIM1CYP1A2ELANEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020065408-A1 | SULFOMALEIMIDE-BASED LINKERS AND CORRESPONDING CONJUGATES | PIERRE FABRE MEDICAMENT (FR) | 2020-04-02 | — | — | WO | disclosed |