SCHEMBL21886989

SCHEMBL21886989

CC(C)(C)OC(=O)N1CC[C@H](Oc2ccc(C#N)cc2F)C1

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 9/20 0.56
PDE4B Q07343 1/20 0.48
USP30 Q70CQ3 1/20 0.47
GPR6 P46095 6/20 0.47
PIK3CD O00329 2/20 0.46
PIK3CA P42336 2/20 0.46
PIK3CB P42338 2/20 0.46
PIK3CG P48736 2/20 0.46
ALK Q9UM73 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL223791 0.94 GPR119 (0.64) GPR119PDE4BGPR6ALK
SCHEMBL21824767 0.85 USP30 (0.50) USP30GPR6
SCHEMBL28719769 0.84 GPR119 (0.58) GPR119PDE4BUSP30PIK3CDPIK3CA
SCHEMBL30140331 0.84 GPR119 (0.58) GPR119PDE4BUSP30PIK3CDPIK3CA
SCHEMBL20439351 0.84 GPR119 (0.58) GPR119PDE4BUSP30PIK3CDPIK3CA
SCHEMBL29363719 0.84 GPR119 (0.58) GPR119PDE4BUSP30PIK3CDPIK3CA
SCHEMBL20439353 0.84 GPR119 (0.58) GPR119PDE4BUSP30PIK3CDPIK3CA
SCHEMBL13419720 0.84 GPR119 (0.58) GPR119PDE4BUSP30PIK3CDPIK3CA
SCHEMBL27150331 0.82 GPR119 (0.47) GPR119USP30GPR6ALK
SCHEMBL24117836 0.82 GPR119 (0.79) GPR119USP30PIK3CDALK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210392895-A1 NOVEL OXADIAZOLES PI INDUSTRIES LIMITED (IN) 2021-12-23 US disclosed
WO-2020070610-A1 NOVEL OXADIAZOLES PI INDUSTRIES LTD. (IN) 2020-04-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210392895-A1 NOVEL OXADIAZOLES OXA1L, CYP1B1, CYP1A1 GPR119 741/4885PDE4B 503/4885USP30 4128/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.