Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 2/20 | 0.54 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.53 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21824790 | 0.93 | GPR119 (0.61) | CHEK2GPR119PDE4BPDE4APDE4C | |
| SCHEMBL21825204 | 0.91 | CHEK2 (0.48) | CHEK2GPR119USP30PDE4B | |
| SCHEMBL21887531 | 0.91 | CHEK2 (0.48) | CHEK2GPR119USP30PDE4B | |
| SCHEMBL21824928 | 0.87 | USP30 (0.50) | CHEK2GPR119USP30PIK3CDPDE4B | |
| SCHEMBL5545000 | 0.85 | USP30 (0.58) | CHEK2GPR119USP30PIK3CD | |
| SCHEMBL5544755 | 0.85 | USP30 (0.58) | CHEK2GPR119USP30PIK3CD | |
| SCHEMBL240368 | 0.85 | USP30 (0.58) | CHEK2GPR119USP30PIK3CD | |
| SCHEMBL699609 | 0.85 | GPR119 (0.58) | CHEK2GPR119USP30PIK3CDPDE4B | |
| SCHEMBL15376614 | 0.85 | GPR119 (0.58) | CHEK2GPR119USP30PIK3CDPDE4B | |
| SCHEMBL699608 | 0.85 | GPR119 (0.58) | CHEK2GPR119USP30PIK3CDPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020070610-A1 | NOVEL OXADIAZOLES | PI INDUSTRIES LTD. (IN) | 2020-04-09 | — | — | WO | disclosed |