Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 3/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14051608 | 0.82 | CYP1A2 (0.39) | CYP1A2CYP2C19MEN1KMT2ACYP3A4 | |
| SCHEMBL13082493 | 0.78 | CYP1A2 (0.37) | CYP1A2CYP2C19MEN1KMT2ACYP3A4 | |
| SCHEMBL3652252 | 0.78 | ESR1 (0.42) | ARMEN1KMT2AESR1ESR2 | |
| SCHEMBL17545789 | 0.77 | TSHR (0.41) | ARCYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL8811100 | 0.77 | ESR1 (0.42) | ARMEN1KMT2AUPP1ESR1 | |
| SCHEMBL21811303 | 0.75 | IL4 (0.38) | ARMEN1KMT2AESR1ESR2 | |
| SCHEMBL17929420 | 0.75 | AR (0.37) | ARMEN1KMT2AESR1ESR2 | |
| SCHEMBL423158 | 0.75 | AR (0.37) | ARMEN1KMT2AESR1ESR2 | |
| SCHEMBL21284909 | 0.75 | CYP1A2 (0.35) | CYP1A2CYP2C19MEN1KMT2ACYP3A4 | |
| SCHEMBL7975208 | 0.74 | CYP1A2 (0.46) | CYP1A2CYP2C19MEN1KMT2AUPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024099269-A1 | ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, USE THEREOF | 华东师范大学 | 2024-05-16 | — | — | WO | disclosed |
| CN-118026880-A | Aryl amide compound, pharmaceutical composition containing same and application thereof | 华东师范大学 | 2024-05-14 | — | — | CN | disclosed |
| WO-2020057511-A1 | QUINAZOLINE DERIVATIVES AS ANTITUMOR AGENTS | SUZHOU ZANRONG PHARMA LIMITED (CN) | 2020-03-26 | — | — | WO | disclosed |