Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.45 |
| ▸ | NOS1 | P29475 | 3/20 | 0.45 |
| ▸ | NOS2 | P35228 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.41 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.37 |
| ▸ | CHRNG | P07510 | 1/20 | 0.37 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | CHRND | Q07001 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28823769 | 0.90 | SLC6A2 (0.50) | NOS3NOS1NOS2SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL23302664 | 0.89 | SLC6A2 (0.49) | NOS3NOS1NOS2SLC6A4SLC6A2 | |
| SCHEMBL31142581 | 0.80 | CHEK2 (0.42) | NOS3NOS1NOS2SLC6A4SLC6A2 | |
| SCHEMBL3619850 | 0.80 | SLC6A4 (0.48) | SLC6A4SLC6A2SLC6A3CHEK2 | |
| SCHEMBL148917 | 0.78 | MAOA (0.46) | SLC6A4SLC6A2JAK2JAK1JAK3 | |
| SCHEMBL23632725 | 0.77 | HTR2C (0.47) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6895622 | 0.77 | CHRM5 (0.41) | NOS3NOS1NOS2SLC6A4SLC6A2 | |
| SCHEMBL16371014 | 0.74 | MAPT (0.42) | SLC6A4SLC6A2SLC6A3CHRNB4CHRNA3 | |
| SCHEMBL16371016 | 0.74 | MAPT (0.42) | SLC6A4SLC6A2SLC6A3CHRNB4CHRNA3 | |
| SCHEMBL16391137 | 0.74 | MAPT (0.42) | SLC6A4SLC6A2SLC6A3CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020070610-A1 | NOVEL OXADIAZOLES | PI INDUSTRIES LTD. (IN) | 2020-04-09 | — | — | WO | disclosed |