Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | EIF4E | P06730 | 1/20 | 0.48 |
| ▸ | TOP1 | P11387 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | PNP | P00491 | 3/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21888092 | 1.00 | LMNA (0.48) | LMNASMN1; SMN2ADORA1ALDH1A1CYP3A4 | |
| SCHEMBL13886984 | 0.89 | LMNA (0.54) | LMNASMN1; SMN2ADORA1ALDH1A1CYP3A4 | |
| SCHEMBL11996917 | 0.89 | LMNA (0.54) | LMNASMN1; SMN2ADORA1ALDH1A1CYP3A4 | |
| SCHEMBL13186252 | 0.89 | LMNA (0.54) | LMNASMN1; SMN2ADORA1ALDH1A1CYP3A4 | |
| SCHEMBL10283916 | 0.88 | LMNA (0.47) | LMNASMN1; SMN2ADORA1ALDH1A1CYP3A4 | |
| SCHEMBL21888094 | 0.85 | LMNA (0.44) | LMNASMN1; SMN2ADORA1ALDH1A1CYP3A4 | |
| SCHEMBL21887923 | 0.83 | LMNA (0.43) | LMNASMN1; SMN2ADORA1ALDH1A1CYP3A4 | |
| SCHEMBL21888945 | 0.83 | LMNA (0.43) | LMNASMN1; SMN2ADORA1ALDH1A1CYP3A4 | |
| SCHEMBL14304821 | 0.82 | LMNA (0.41) | LMNASMN1; SMN2ADORA1ALDH1A1CYP3A4 | |
| SCHEMBL21887965 | 0.82 | LMNA (0.42) | LMNASMN1; SMN2ADORA1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020072931-A2 | PRE-ACTIVATED NUCLEOSIDE IMPDH INHIBITORS AS ANTI-INFECTIVE DRUGS | OCTAGON THERAPEUTICS INC. (US) | 2020-04-09 | — | — | WO | disclosed |