SCHEMBL218883

SCHEMBL218883

CC(=O)Oc1cc2cccc3ccc4c(S(=O)(=O)Cl)c(S(=O)(=O)Cl)c(S(=O)(=O)Cl)c1c4c32

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.45
MAPT P10636 5/20 0.45
ALDH1A1 P00352 4/20 0.45
L3MBTL1 Q9Y468 4/20 0.45
KDM4E B2RXH2 3/20 0.45
TDP1 Q9NUW8 2/20 0.45
GAA P10253 2/20 0.45
POLB P06746 2/20 0.45
APEX1 P27695 1/20 0.45
RECQL P46063 1/20 0.45
BLM P54132 1/20 0.45
HPGD P15428 2/20 0.35
CA12 O43570 1/20 0.35
CA9 Q16790 1/20 0.35
MEN1 O00255 6/20 0.34
TSHR P16473 1/20 0.34
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
NFKB1 P19838 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4444803 0.84 KMT2A (0.46) KMT2AMAPTALDH1A1L3MBTL1KDM4E
Hydrochloric Acid SCHEMBL9073780 0.83 KMT2A (0.45) KMT2AMAPTALDH1A1L3MBTL1KDM4E
SCHEMBL9506000 0.83 KMT2A (0.45) KMT2AMAPTALDH1A1L3MBTL1KDM4E
Hydrochloric Acid SCHEMBL303051 0.83 KMT2A (0.45) KMT2AMAPTALDH1A1L3MBTL1KDM4E
SCHEMBL9073806 0.82 KMT2A (0.44) KMT2AMAPTALDH1A1L3MBTL1KDM4E
SCHEMBL4450226 0.80 ALDH1A1 (0.49) KMT2AMAPTALDH1A1L3MBTL1KDM4E
SCHEMBL216727 0.79 KMT2A (0.35) KMT2AMAPTALDH1A1L3MBTL1KDM4E
SCHEMBL9689252 0.78 ALDH1A1 (0.37) KMT2AMAPTALDH1A1L3MBTL1KDM4E
SCHEMBL5693209 0.76 CYP1A2 (0.38) KMT2AALDH1A1L3MBTL1TDP1HPGD
SCHEMBL9962926 0.76 KMT2A (0.42) KMT2AMAPTALDH1A1L3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0789839-B1 ION SENSOR AND A METHOD FOR PRODUCING SAME MINNESOTA MINING & MFG (US) 1999-12-01 EP claimed
EP-0789839-A1 ION SENSOR AND A METHOD FOR PRODUCING SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-08-20 EP claimed
US-5591400-A Method for producing an ionic sensor MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-01-07 US claimed
WO-1996013711-A1 ION SENSOR AND A METHOD FOR PRODUCING SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-05-09 WO claimed
EP-2545373-B1 MEASURING ANALYTE CONCENTRATION INCORPORATING TEMPERATURE AND PH CORRECTION MEDTRONIC MINIMED INC (US) 2022-08-24 EP disclosed
EP-2751577-B1 A method of manufacturing a sterilized optical analyte sensor MEDTRONIC MINIMED INC (US) 2019-04-17 EP disclosed
EP-2989975-B1 OPTICAL SYSTEMS AND METHODS FOR RATIONMETRIC MEASUREMENT OF BLOOD GLUCOSE CONCENTRATION MEDTRONIC MINIMED INC (US) 2018-06-13 EP disclosed
US-9839378-B2 Optical systems and methods for ratiometric measurement of blood glucose concentration MEDTRONIC MINIMED, INC. (US) 2017-12-12 US disclosed
US-9757057-B2 Dry insertion and one-point in vivo calibration of an optical analyte sensor MEDTRONIC MINIMED, INC. (US) 2017-09-12 US disclosed
US-9693720-B2 Equilibrium non-consuming fluorescence sensor for real time intravascular glucose measurement MEDTRONIC MINIMED, INC. (US) 2017-07-04 US disclosed
EP-2989975-A1 OPTICAL SYSTEMS AND METHODS FOR RATIONMETRIC MEASUREMENT OF BLOOD GLUCOSE CONCENTRATION Medtronic MiniMed, Inc. (US) 2016-03-02 EP disclosed
EP-2916722-A1 DRY INSERTION AND ONE-POINT IN VIVO CALIBRATION OF AN OPTICAL ANALYTE SENSOR Medtronic MiniMed, Inc. (US) 2015-09-16 EP disclosed
EP-0263693-B1 MICRO SENSOR MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-06-02 EP disclosed
US-5081041-A IONIC COMPONENT SENSOR AND METHOD FOR MAKING AND USING SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-01-14 US disclosed
EP-0450519-A2 Ionic component sensor and method for making and using same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-10-09 EP disclosed
US-4999306-A Composition, apparatus and method for sensing ionic components MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-03-12 US disclosed
US-4886338-A Optical fiber event sensor MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-12-12 US disclosed
EP-0340018-A2 Composition, apparatus and method for sensing ionic components MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-11-02 EP disclosed
US-4798738-A HYDROPHILIC POLYMER, DYE, OPTICAL FIBER, PH CARDIOVASCULAR DEVICES, INC. (US) 1989-01-17 US disclosed
EP-0263693-A2 Micro sensor MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-04-13 EP disclosed