SCHEMBL21889546

SCHEMBL21889546

OCCn1nc(-c2ccc(OCc3ccccc3)cc2)nc1C1CC1

nearest known ligand 0.61

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 8/20 0.61
MAOB P27338 3/20 0.57
FDFT1 P37268 1/20 0.45
IGF1R P08069 1/20 0.44
PRMT5 O14744 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21914530 0.86 AOC3 (0.59) AOC3MAOBFDFT1IGF1RPRMT5
SCHEMBL25835186 0.84 AOC3 (0.57) AOC3MAOBFDFT1IGF1RPRMT5
SCHEMBL21889505 0.83 AOC3 (0.62) AOC3MAOBFDFT1IGF1RPRMT5
SCHEMBL21889547 0.81 AOC3 (0.57) AOC3
SCHEMBL21915134 0.79 AOC3 (0.59) AOC3MAOBFDFT1IGF1RPRMT5
SCHEMBL21889007 0.76 AOC3 (1.00) AOC3
SCHEMBL22139719 0.70 AOC3 (0.47) AOC3
SCHEMBL22139724 0.69 AOC3 (0.49) AOC3
SCHEMBL2036841 0.69 NR1H3 (0.44) MAOB
SCHEMBL9113076 0.68 FFAR1 (0.44) MAOBFDFT1PRMT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3626699-B1 SSAO INHIBITOR SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) 2023-07-12 EP disclosed
US-20210198220-A1 SSAO INHIBITOR SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) 2021-07-01 US disclosed
US-11001563-B2 SSAO inhibitor SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) 2021-05-11 US disclosed
US-20200115352-A1 SSAO INHIBITOR SHANDONG DANHONG PHARMACEUTICAL CO., LTD. 2020-04-16 US disclosed
EP-3626699-A1 SSAO INHIBITOR Shandong Danhong Pharmaceutical Co., Ltd. (CN) 2020-03-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11001563-B2 SSAO inhibitor SSB, ASAH2, AOX1 AOC3 53/4885MAOB 78/4885FDFT1 185/4885
US-20210198220-A1 SSAO INHIBITOR SSB, ASAH2, AOX1 AOC3 53/4885MAOB 78/4885FDFT1 185/4885
US-20200115352-A1 SSAO INHIBITOR SSB, ASAH2, AOX1 AOC3 53/4885MAOB 78/4885FDFT1 185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.