SCHEMBL21889843

SCHEMBL21889843

CC(C)(C)OC(=O)NC/C(=C\F)COc1ccc(C=O)cc1

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.45
AOC3 Q16853 2/20 0.45
ALDH1A1 P00352 5/20 0.44
KDM4E B2RXH2 1/20 0.44
CA12 O43570 5/20 0.40
CA1 P00915 5/20 0.40
CA2 P00918 5/20 0.40
CA9 Q16790 5/20 0.40
AOC2 O75106 2/20 0.38
MEN1 O00255 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
KMT2A Q03164 1/20 0.38
DAO P14920 1/20 0.37
MAOA P21397 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23329639 0.88 MAOB (0.46) MAOBAOC3CA12CA1CA2
SCHEMBL21768043 0.86 AOC3 (0.50) MAOBAOC3CA12CA1CA2
SCHEMBL21780054 0.86 AOC3 (0.50) MAOBAOC3CA12CA1CA2
SCHEMBL23718599 0.86 AOC3 (0.50) MAOBAOC3CA12CA1CA2
SCHEMBL21780044 0.85 AOC3 (0.49) MAOBAOC3ALDH1A1CA12CA1
SCHEMBL23718635 0.85 AOC3 (0.49) MAOBAOC3ALDH1A1CA12CA1
SCHEMBL28367255 0.85 AOC3 (0.44) MAOBAOC3ALDH1A1KDM4ECA12
SCHEMBL21768135 0.85 AOC3 (0.49) MAOBAOC3ALDH1A1CA12CA1
SCHEMBL21889186 0.85 AOC3 (0.44) MAOBAOC3ALDH1A1KDM4ECA12
SCHEMBL31603798 0.84 MAOB (0.35) MAOBAOC3ALDH1A1KDM4ECA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025107036-A1 DUAL INHIBITORS OF AMINE OXIDASES AND PEROXIDASES, AND USES THEREOF SYNTARA LIMITED (AU) 2025-05-30 WO disclosed
EP-3626699-B1 SSAO INHIBITOR SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) 2023-07-12 EP disclosed
US-20210198220-A1 SSAO INHIBITOR SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) 2021-07-01 US disclosed
US-11001563-B2 SSAO inhibitor SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) 2021-05-11 US disclosed
US-20200115352-A1 SSAO INHIBITOR SHANDONG DANHONG PHARMACEUTICAL CO., LTD. 2020-04-16 US disclosed
EP-3626699-A1 SSAO INHIBITOR Shandong Danhong Pharmaceutical Co., Ltd. (CN) 2020-03-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11001563-B2 SSAO inhibitor SSB, ASAH2, AOX1 MAOB 78/4885AOC3 53/4885ALDH1A1 177/4885
US-20210198220-A1 SSAO INHIBITOR SSB, ASAH2, AOX1 MAOB 78/4885AOC3 53/4885ALDH1A1 177/4885
US-20200115352-A1 SSAO INHIBITOR SSB, ASAH2, AOX1 MAOB 78/4885AOC3 53/4885ALDH1A1 177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.