Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9362996 | 0.82 | ACHE (0.56) | ACHE | |
| Hydrochloric Acid SCHEMBL9359043 | 0.80 | ACHE (0.54) | ACHE | |
| Fumaric Acid SCHEMBL9359036 | 0.78 | ACHE (0.50) | ACHE | |
| Fumaric Acid SCHEMBL9358712 | 0.78 | ACHE (0.50) | ACHE | |
| SCHEMBL12719136 | 0.78 | ACHE (0.55) | ACHE | |
| SCHEMBL5361048 | 0.77 | ACHE (0.54) | ACHE | |
| SCHEMBL5350686 | 0.76 | ACHE (0.52) | ACHE | |
| SCHEMBL16141531 | 0.75 | ACHE (0.56) | ACHE | |
| SCHEMBL4853298 | 0.75 | ACHE (0.55) | ACHE | |
| SCHEMBL10696327 | 0.74 | ACHE (0.59) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632439-A1 | DEMENTIA THERAPEUTIC AGENT COMBINING PYRAZOLOQUINOLINE DERIVATIVE AND DONEPEZIL | Eisai R&D Management Co., Ltd. (JP) | 2020-04-08 | — | — | EP | disclosed |