Orotidine Monophosphate

Orotidine Monophosphate

SCHEMBL21891

O=C(O)c1cc(=O)[nH]c(=O)n1[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]1O

nearest known ligand 0.73

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Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 8/20 0.58
UMPS P11172 4/20 0.58
DNPH1 O43598 1/20 0.52
P2RY6 Q15077 6/20 0.50
P2RX3 P56373 1/20 0.49
P2RY4 P51582 3/20 0.49
P2RY14 Q15391 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Orotidine Monophosphate SCHEMBL12727823 1.00 P2RY2 (0.58) P2RY2UMPSDNPH1P2RY6P2RX3
Orotidine Monophosphate SCHEMBL30969958 0.99 P2RY2 (0.57) P2RY2UMPSDNPH1P2RY6P2RX3
Orotidine Monophosphate SCHEMBL20266267 0.99 P2RY2 (0.57) P2RY2UMPSDNPH1P2RY6P2RX3
SCHEMBL18453338 0.92 P2RY2 (0.70) P2RY2P2RY6P2RX3P2RY4P2RY14
SCHEMBL1398653 0.92 P2RY2 (0.54) P2RY2UMPSDNPH1P2RY6P2RX3
SCHEMBL3514478 0.90 P2RY2 (0.73) P2RY2P2RY6P2RX3P2RY4P2RY14
SCHEMBL1363155 0.89 P2RY2 (0.60) P2RY2UMPSDNPH1P2RY6P2RY4
SCHEMBL12143856 0.89 P2RY2 (0.60) P2RY2UMPSDNPH1P2RY6P2RY4
SCHEMBL12143130 0.89 P2RY2 (0.60) P2RY2UMPSDNPH1P2RY6P2RY4
SCHEMBL12143135 0.87 UMPS (0.58) P2RY2UMPSDNPH1P2RY6P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2211 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250313852-A1 BIDIRECTIONAL CHEF1 VECTORS AGC BIOLOGICS INC (US) 2025-10-09 US claimed
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE TEAM MEDICAL, LLC 2025-09-18 US claimed
US-20250145981-A1 CHEMOENZYMATIC CARBOXYLATION COMPOSITIONS AND METHODS SOLUGEN, INC. (US) 2025-05-08 US claimed
CN-119432702-A Uracil producing strain, construction method and application thereof 新疆瑞诺生物科技有限公司 2025-02-14 CN claimed
CN-118620816-B Uridine producing strain, construction method and application thereof 天津科技大学 2024-10-29 CN claimed
CN-118620816-A Uridine producing strain, construction method and application thereof 天津科技大学 2024-09-10 CN claimed
CN-118272285-B Uracil nucleotide production strain, directional transformation method and application thereof 天津科技大学 2024-08-16 CN claimed
CN-118302514-A Acid-resistant yeast strain for high yield of L-malic acid, construction method and application thereof 中国科学院天津工业生物技术研究所 2024-07-05 CN claimed
CN-118272285-A Uracil nucleotide production strain, directional transformation method and application thereof 天津科技大学 2024-07-02 CN claimed
CN-117467551-A Acid-resistant yeast strain for high yield of L-malic acid, construction method and application thereof 中国科学院天津工业生物技术研究所 2024-01-30 CN claimed
US-20030158140-A1 Splicing as target for identifying new active substances BAYER AKTIENGESELLSCHAFT (DE) 2003-08-21 US claimed
EP-1325959-A1 TRANSFORMATION SYSTEM OF FUNGUS BELONGING TO THE GENUS MONASCUS KYOWA HAKKO KOGYO CO., LTD. (JP) 2003-07-09 EP claimed
EP-1255567-A1 SELECTIVE CELLULAR TARGETING: MULTIFUNCTIONAL DELIVERY VEHICLES Drug Innovation & Design, Inc. (US) 2002-11-13 EP claimed
WO-2001077366-A1 POSITIVE SELECTION METHOD, COMPOUNDS, HOST CELLS AND USES THEREOF CUBIST PHARMACEUTICALS, INC. (US) 2001-10-18 WO claimed
WO-2001036003-A2 SELECTIVE CELLULAR TARGETING: MULTIFUNCTIONAL DELIVERY VEHICLES DRUG INNOVATION & DESIGN, INC. (US) 2001-05-25 WO claimed
EP-0504279-B1 FERMENTATION PROCESS FOR THE PRODUCTION OF PYRIMIDINE DEOXYRIBONUCLEOSIDES CHEMGEN CORP (US) 1997-07-09 EP claimed
US-5213972-A Production of thymidine and deoxyuridine, intermediates for AZT CHEMGEN CORPORATION (US) 1993-05-25 US claimed
EP-0504279-A4 FERMENTATION PROCESS FOR THE PRODUCTION OF PYRIMIDINE DEOXYRIBONUCLEOSIDES 1993-02-17 EP claimed
EP-0504279-A1 FERMENTATION PROCESS FOR THE PRODUCTION OF PYRIMIDINE DEOXYRIBONUCLEOSIDES. CHEMGEN CORP (US) 1992-09-23 EP claimed
WO-1991009130-A1 FERMENTATION PROCESS FOR THE PRODUCTION OF PYRIMIDINE DEOXYRIBONUCLEOSIDES CHEMGEN CORPORATION (US) 1991-06-27 WO claimed