SCHEMBL218910

SCHEMBL218910

NNC(=O)C(O)C(O)C(=O)NN

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 1.00
TSHR P16473 2/20 0.41
CYP1A2 P05177 1/20 0.41
NFKB1 P19838 1/20 0.41
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
THPO P40225 1/20 0.41
ALDH1A1 P00352 2/20 0.39
MEN1 O00255 1/20 0.39
USP2 O75604 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
LMNA P02545 1/20 0.39
CTSD P07339 1/20 0.39
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
P2RX7 Q99572 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL714549 1.00 HIF1A (1.00) HIF1ATSHRCYP1A2NFKB1MAOA
SCHEMBL20404646 0.88 HIF1A (0.78) HIF1ATSHRCYP1A2NFKB1MAOA
SCHEMBL11228168 0.88 HIF1A (0.78) HIF1ATSHRCYP1A2NFKB1MAOA
SCHEMBL18237282 0.88 HIF1A (0.78) HIF1ATSHRCYP1A2NFKB1MAOA
SCHEMBL16569851 0.87 HIF1A (0.77) HIF1ATSHRCYP1A2NFKB1MAOA
SCHEMBL7645290 0.87 HIF1A (0.77) HIF1ATSHRCYP1A2NFKB1MAOA
SCHEMBL11059304 0.87 HIF1A (0.77) HIF1ATSHRCYP1A2NFKB1MAOA
SCHEMBL12703862 0.86 HIF1A (0.74) HIF1ATSHRCYP1A2NFKB1MAOA
SCHEMBL6928168 0.84 HIF1A (0.70) HIF1ATSHRCYP1A2NFKB1MAOA
SCHEMBL6580898 0.79 HIF1A (0.65) HIF1ATSHRCYP1A2NFKB1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 652 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080895-A Polyglycolic acid composition and preparation method thereof, biodegradable polyester material and application thereof, and PGA temporary plugging ball and preparation method thereof 2026-05-26 CN claimed
CN-122011806-A Preparation method of flaky magnesium hydroxide flame retardant 山东艾科高分子材料有限公司 2026-05-12 CN claimed
CN-115337800-B High-desalination antioxidant polyamide reverse osmosis membrane, preparation method and application thereof 万华化学集团股份有限公司 2024-05-03 CN claimed
CN-114478829-B Hyaluronic acid crosslinked active material composition, preparation method and application 常州百瑞吉生物医药有限公司 2023-07-28 CN claimed
EP-3472214-B1 AQUEOUS POLYMER DISPERSION AND AQUEOUS COATING COMPOSITION COMPRISING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2023-07-12 EP claimed
CN-114350035-B Hyaluronic acid crosslinking active material and application thereof 常州百瑞吉生物医药有限公司 2023-04-25 CN claimed
CN-114621407-B Preparation and application of azine-based COFs covalent organic framework material 中国科学院大连化学物理研究所 2023-03-28 CN claimed
CN-115337800-A High-desalination antioxidant polyamide reverse osmosis membrane, and preparation method and application thereof 万华化学集团股份有限公司 2022-11-15 CN claimed
CN-114014972-B Ketone hydrazine crosslinking system for organic carrier in photovoltaic silver paste 上海银浆科技有限公司 2022-11-08 CN claimed
CN-114316087-B Hyaluronic acid cross-linking active material, preparation method and application thereof 常州百瑞吉生物医药有限公司 2022-10-28 CN claimed
WO-2011160641-A2 HYDROPHILIC GELS FROM POLYURETHANE-BASED PHOTOINITIATORS COLOPLAST A/S (DK) 2011-12-29 WO claimed
EP-2246403-A1 Waterborne adhesive formulations Akzo Nobel Coatings International B.V. (NL) 2010-11-03 EP claimed
US-7625638-B2 moisture-absorbent sheet; body comprising oxalic acid dihydrazide, a hygroscopic agent, and a resin selecting from fluororesins, polyacrylonitrile resins, polyamide resins; suppressing the formation of dark spots in the organic electroluminescent device DYNIC CORPORATION (JP) 2009-12-01 US claimed
EP-1012208-A4 CROSS-LINKED PARTICLES ACCESS PHARMACEUTICALS AUSTRAL (AU) 2003-06-18 EP claimed
US-6221397-B1 POLYMER CONTAINING REACTIVE GROUPS SELECTED FROM THE GROUP CONSISTING OF CARBOXYL, HYDRAZIDYL, AMINO AND THIOL GROUPS, COVALENTLY LINKED TO A DIHYDRAZIDE SPACER BIOTECH AUSTRALIA PTY LIMITED (AU) 2001-04-24 US claimed
EP-1012208-A1 CROSS-LINKED PARTICLES BIOTECH AUSTRALIA PTY. LIMITED (AU) 2000-06-28 EP claimed
WO-1999011703-A1 CROSS-LINKED PARTICLES BIOTECH AUSTRALIA PTY. LIMITED (US) 1999-03-11 WO claimed
US-4722946-A MIXTURE OF HIGH AND LOW-MOLECULAR WEIGHT DIOLS POLYMER DYNAMICS (DELAWARE), LTD. (US) 1988-02-02 US claimed
US-4714648-A EPOXY RESIN, HYDRAZINE HARDENER, ALCOHOL, UREA COMPOUND TOHO RAYON CO., LTD. (JP) 1987-12-22 US claimed
US-4410457-A EPOXY REACTIVE SOLVENT, EPOXY RESIN, LATENT HARDENER, EPOXIDE-DIALKYLAMINE ADDUCT SUMITOMO CHEMICAL CO., LTD. (JP) 1983-10-18 US claimed