Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | KDM5C | P41229 | 1/20 | 0.54 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.54 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.54 |
| ▸ | CTSD | P07339 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL714549 | 0.84 | HIF1A (1.00) | HIF1ACTSDALDH1A1MAPTCYP1A2 | |
| SCHEMBL218910 | 0.84 | HIF1A (1.00) | HIF1ACTSDALDH1A1MAPTCYP1A2 | |
| SCHEMBL220310 | 0.81 | KDM4E (0.77) | HIF1AKDM4EKDM5CPHF8KDM2A | |
| SCHEMBL5858599 | 0.81 | HIF1A (0.50) | HIF1AKDM4EKDM5CPHF8KDM2A | |
| Hydrazine SCHEMBL28064827 | 0.78 | KDM4E (0.72) | HIF1AKDM4EKDM5CPHF8KDM2A | |
| SCHEMBL11228168 | 0.74 | HIF1A (0.78) | HIF1ACTSDALDH1A1MAPTCYP1A2 | |
| SCHEMBL20404646 | 0.74 | HIF1A (0.78) | HIF1ACTSDALDH1A1MAPTCYP1A2 | |
| SCHEMBL18237282 | 0.74 | HIF1A (0.78) | HIF1ACTSDALDH1A1MAPTCYP1A2 | |
| SCHEMBL3694155 | 0.73 | KDM4E (0.46) | HIF1AKDM4EKDM5CPHF8KDM2A | |
| SCHEMBL9015312 | 0.73 | HIF1A (0.52) | HIF1AKDM4EKDM5CPHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1012208-A4 | CROSS-LINKED PARTICLES | ACCESS PHARMACEUTICALS AUSTRAL (AU) | 2003-06-18 | — | — | EP | disclosed |
| US-6221397-B1 | POLYMER CONTAINING REACTIVE GROUPS SELECTED FROM THE GROUP CONSISTING OF CARBOXYL, HYDRAZIDYL, AMINO AND THIOL GROUPS, COVALENTLY LINKED TO A DIHYDRAZIDE SPACER | BIOTECH AUSTRALIA PTY LIMITED (AU) | 2001-04-24 | — | — | US | disclosed |
| EP-1012208-A1 | CROSS-LINKED PARTICLES | BIOTECH AUSTRALIA PTY. LIMITED (AU) | 2000-06-28 | — | — | EP | disclosed |
| WO-1999011703-A1 | CROSS-LINKED PARTICLES | BIOTECH AUSTRALIA PTY. LIMITED (US) | 1999-03-11 | — | — | WO | disclosed |