Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 8/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2188565 | 0.89 | CHRM4 (0.47) | CHRM4DRD2DRD3KMT2ALMNA | |
| SCHEMBL2189156 | 0.87 | HSD17B10 (0.52) | KMT2ALMNATSHRHSD17B10MEN1 | |
| SCHEMBL2187717 | 0.86 | LMNA (0.53) | KMT2ALMNATSHRHSD17B10MEN1 | |
| SCHEMBL2185757 | 0.85 | LMNA (0.66) | CHRM4KMT2ALMNATSHRHSD17B10 | |
| SCHEMBL2186962 | 0.85 | LMNA (0.56) | KMT2ALMNATSHRHSD17B10MEN1 | |
| SCHEMBL2188261 | 0.84 | LMNA (0.56) | KMT2ALMNATSHRHSD17B10MEN1 | |
| SCHEMBL2185672 | 0.84 | LMNA (0.53) | KMT2ALMNATSHRHSD17B10MEN1 | |
| SCHEMBL2188122 | 0.83 | LMNA (0.55) | KMT2ALMNATSHRHSD17B10MEN1 | |
| SCHEMBL2188250 | 0.83 | LMNA (0.51) | KMT2ALMNATSHRHSD17B10MEN1 | |
| SCHEMBL2185664 | 0.83 | TSHR (0.50) | KMT2ALMNATSHRHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343293-A1 | NOVEL PIPERIDIN-4-YL-THIAZOLE-CARBOXAMIDE ANALOGUES AS INHIBITORS OF T-CELL PROLIFERATION AND USES THEREOF | 4SC AG (DE) | 2011-07-13 | — | — | EP | disclosed |