Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PPID | Q08752 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23423232 | 1.00 | POLB (0.45) | POLBGAABCL2SIRT1CYP3A4 | |
| SCHEMBL21891811 | 0.92 | POLB (0.49) | POLBGAABCL2SIRT1CYP3A4 | |
| SCHEMBL23130334 | 0.86 | NPC1 (0.41) | POLBGAABCL2CYP3A4CYP2C19 | |
| SCHEMBL21891858 | 0.85 | PPID (0.52) | POLBGAABCL2CYP3A4CYP2C19 | |
| SCHEMBL21891818 | 0.85 | SIRT1 (0.52) | SIRT1SIRT2 | |
| SCHEMBL23130277 | 0.84 | SIRT1 (0.56) | SIRT1SIRT2 | |
| SCHEMBL21802411 | 0.84 | SIRT1 (0.56) | SIRT1SIRT2 | |
| SCHEMBL21891750 | 0.83 | SIRT1 (0.43) | GAASIRT1CYP1A2SIRT2NPC1 | |
| SCHEMBL1839387 | 0.82 | NPSR1 (0.53) | GAACA1 | |
| SCHEMBL5259541 | 0.82 | NPSR1 (0.53) | GAACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230021574-A1 | METHOD FOR PRODUCING ISOCYANATE | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2023-01-26 | — | — | US | disclosed |
| WO-2021100131-A1 | METHOD FOR PRODUCING ISOCYANATE | 旭化成株式会社 | 2021-05-27 | — | — | WO | disclosed |
| US-10968168-B2 | Isocyanate production method | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2021-04-06 | — | — | US | disclosed |
| EP-3626705-B1 | ISOCYANATE PRODUCTION METHOD | ASAHI CHEMICAL IND (JP) | 2021-03-24 | — | — | EP | disclosed |
| US-20200115327-A1 | ISOCYANATE PRODUCTION METHOD | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2020-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200115327-A1 | ISOCYANATE PRODUCTION METHOD | IDH3A, ALKBH3, CPS1 | POLB 376/4885GAA 1174/4885BCL2 2467/4885 |
| US-10968168-B2 | Isocyanate production method | IDH3A, ALKBH3, CPS1 | POLB 376/4885GAA 1174/4885BCL2 2467/4885 |
| US-20230021574-A1 | METHOD FOR PRODUCING ISOCYANATE | CPS1, IDH3A, ALKBH3 | POLB 861/4885GAA 1251/4885BCL2 1781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.