SCHEMBL2189184

SCHEMBL2189184

c1ccc2nc(-c3n[nH]c4ccccc34)ccc2c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 1/20 0.55
FLT1 P17948 1/20 0.55
LRRK2 Q5S007 2/20 0.54
ALDH1A1 P00352 4/20 0.53
KDM4E B2RXH2 4/20 0.53
HPGD P15428 3/20 0.53
IDO1 P14902 3/20 0.53
GAA P10253 2/20 0.53
MAPK10 P53779 2/20 0.53
ALPL P05186 1/20 0.53
TTK P33981 1/20 0.53
ITK Q08881 3/20 0.51
NPC1 O15118 3/20 0.50
RAB9A P51151 3/20 0.50
PKM P14618 2/20 0.50
TP53 P04637 2/20 0.50
ALOX15 P16050 1/20 0.50
TSHR P16473 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
HSD17B10 Q99714 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29363709 1.00 FGFR1 (0.55) FGFR1FLT1LRRK2ALDH1A1KDM4E
SCHEMBL25029122 0.83 IDO1 (0.54) FGFR1FLT1LRRK2ALDH1A1KDM4E
SCHEMBL29363676 0.83 IDO1 (0.54) FGFR1FLT1LRRK2ALDH1A1KDM4E
SCHEMBL25028603 0.83 IDO1 (0.54) FGFR1FLT1LRRK2ALDH1A1KDM4E
SCHEMBL29361601 0.83 IDO1 (0.54) FGFR1FLT1LRRK2ALDH1A1KDM4E
SCHEMBL29361582 0.81 LRRK2 (0.60) FGFR1FLT1LRRK2ALDH1A1KDM4E
SCHEMBL25027593 0.81 LRRK2 (0.60) FGFR1FLT1LRRK2ALDH1A1KDM4E
SCHEMBL25028595 0.80 LRRK2 (0.50) FGFR1FLT1LRRK2ALDH1A1KDM4E
SCHEMBL29363913 0.80 LRRK2 (0.50) FGFR1FLT1LRRK2ALDH1A1KDM4E
SCHEMBL25029246 0.79 SLC2A1 (0.41) LRRK2ALDH1A1KDM4EHPGDITK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12448368-B2 Indole compounds as androgen receptor modulators NIDO BIOSCIENCES, INC. (US) 2025-10-21 US disclosed
US-20250122176-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES INC (US) 2025-04-17 US disclosed
US-20250092021-A9 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES, INC. 2025-03-20 US disclosed
US-20230348439-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES INC (US) 2023-11-02 US disclosed
US-20230348439-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES INC (US) 2023-11-02 US disclosed
US-20230348439-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES INC (US) 2023-11-02 US disclosed
US-11667624-B2 Indole compounds as androgen receptor modulators NIDO BIOSCIENCES, INC. (US) 2023-06-06 US disclosed
US-11667624-B2 Indole compounds as androgen receptor modulators NIDO BIOSCIENCES, INC. (US) 2023-06-06 US disclosed
US-11667624-B2 Indole compounds as androgen receptor modulators NIDO BIOSCIENCES, INC. (US) 2023-06-06 US disclosed
EP-4182320-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS Nido Biosciences, Inc. (US) 2023-05-24 EP disclosed
US-20120108499-A1 PEPTOID COMPOUNDS UNIVERSITY OF WOLLONGONG (AU) 2012-05-03 US disclosed
EP-2343285-A2 Peptoid compounds UNIVERSITY OF WOLLONGONG (AU) 2011-07-13 EP disclosed
US-20100167995-A1 PEPTOID COMPOUNDS UNIVERSITY OF WOLLONGONG (AU) 2010-07-01 US disclosed
US-7612036-B2 Peptoid compounds UNIVERSITY OF WOLLONGONG (AU) 2009-11-03 US disclosed
EP-1412336-A4 PEPTOID COMPOUNDS UNIV WOLLONGONG (AU) 2007-08-29 EP disclosed
US-20070111927-A1 Peptoid compounds UNIVERSITY OF WOLLONGONG (AU) 2007-05-17 US disclosed
US-7160854-B2 Binaphthyl peptidomimetics for treating vancomycin resistant Staphylococcus aureas infections UNIVERSITY OF WOLLONGONG (AU) 2007-01-09 US disclosed
US-20050043509-A1 Peptoid compounds UNIVERSITY OF WOLLONGONG 2005-02-24 US disclosed
EP-1412336-A1 PEPTOID COMPOUNDS UNIVERSITY OF WOLLONGONG (AU) 2004-04-28 EP disclosed
WO-2003002545-A1 PEPTOID COMPOUNDS UNIVERSITY OF WOLLONGONG (AU) 2003-01-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120108499-A1 PEPTOID COMPOUNDS VIP, FPR1, VIPR1 FGFR1 2764/4885FLT1 1443/4885LRRK2 3545/4885
US-20100167995-A1 PEPTOID COMPOUNDS VIP, FPR1, VIPR1 FGFR1 2764/4885FLT1 1443/4885LRRK2 3545/4885
US-20230348439-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS AR, FSHR, NR5A1 FGFR1 200/4885FLT1 2653/4885LRRK2 160/4885
US-20250122176-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS AR, FSHR, NR5A1 FGFR1 220/4885FLT1 2825/4885LRRK2 186/4885
US-11667624-B2 Indole compounds as androgen receptor modulators AR, FSHR, ADRB3 FGFR1 233/4885FLT1 2807/4885LRRK2 199/4885
US-20070111927-A1 Peptoid compounds VIP, FPR1, VIPR1 FGFR1 2764/4885FLT1 1443/4885LRRK2 3545/4885
US-20250092021-A9 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS AR, FSHR, NR5A1 FGFR1 220/4885FLT1 2825/4885LRRK2 186/4885
US-12448368-B2 Indole compounds as androgen receptor modulators AR, FSHR, ADRB3 FGFR1 233/4885FLT1 2807/4885LRRK2 199/4885
US-20050043509-A1 Peptoid compounds VIP, FPR1, VIPR1 FGFR1 2764/4885FLT1 1443/4885LRRK2 3545/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.