Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21891833 | 0.96 | SIRT1 (0.56) | SIRT1SIRT2 | |
| SCHEMBL21891786 | 0.92 | SIRT1 (0.53) | SIRT1SIRT2 | |
| SCHEMBL23766656 | 0.90 | SIRT1 (0.54) | SIRT1SIRT2 | |
| SCHEMBL23766786 | 0.90 | SIRT1 (0.50) | SIRT1SIRT2 | |
| SCHEMBL21891738 | 0.86 | SIRT1 (0.50) | SIRT1SIRT2 | |
| SCHEMBL21802395 | 0.85 | SIRT1 (0.54) | SIRT1SIRT2 | |
| SCHEMBL21891857 | 0.85 | SIRT1 (0.53) | SIRT1SIRT2NPC1RAB9A | |
| SCHEMBL21891818 | 0.84 | SIRT1 (0.52) | SIRT1SIRT2 | |
| SCHEMBL21891784 | 0.84 | SIRT1 (0.52) | SIRT1SIRT2 | |
| SCHEMBL21802410 | 0.84 | SIRT1 (0.60) | SIRT1SIRT2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10968168-B2 | Isocyanate production method | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2021-04-06 | — | — | US | disclosed |
| US-20200115327-A1 | ISOCYANATE PRODUCTION METHOD | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2020-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200115327-A1 | ISOCYANATE PRODUCTION METHOD | IDH3A, ALKBH3, CPS1 | SIRT1 1448/4885SIRT2 861/4885NPC1 2887/4885 |
| US-10968168-B2 | Isocyanate production method | IDH3A, ALKBH3, CPS1 | SIRT1 1448/4885SIRT2 861/4885NPC1 2887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.