Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.39 |
| ▸ | GCGR | P47871 | 2/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | PAK4 | O96013 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | LTK | P29376 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24213499 | 0.83 | MEN1 (0.38) | DYRK1AMAPK14GCGRRPS6KA3NOTUM | |
| SCHEMBL17619924 | 0.81 | MAPK14 (0.49) | DYRK1ANR4A2MAPK14GCGRDAPK3 | |
| SCHEMBL8360337 | 0.79 | DYRK1A (0.45) | DYRK1ANR4A2MAPK14GCGRDAPK3 | |
| SCHEMBL22309816 | 0.76 | DYRK1A (0.40) | DYRK1ANR4A2MAPK14GCGRDAPK3 | |
| SCHEMBL11537253 | 0.76 | DYRK1A (0.35) | DYRK1ANR4A2MAPK14GCGRDAPK3 | |
| SCHEMBL22310257 | 0.75 | NR4A2 (0.39) | DYRK1ANR4A2MAPK14GCGRDAPK3 | |
| SCHEMBL22309068 | 0.75 | NR4A2 (0.39) | DYRK1ANR4A2MAPK14GCGRDAPK3 | |
| SCHEMBL1554633 | 0.74 | MAPK14 (0.53) | MAPK14GCGRPRKD3MAP4K4MAPK9 | |
| SCHEMBL1776218 | 0.74 | CA12 (0.45) | NR4A2MAPK14GCGRMAP4K4 | |
| SCHEMBL6077530 | 0.74 | MAPK14 (0.53) | MAPK14GCGRPRKD3MAP4K4MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12358878-B2 | N-aromatic amide compounds, preparation methods and uses thereof | SHENZHEN EDK PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2025-07-15 | — | — | US | disclosed |
| EP-3858811-B1 | N-AROMATIC AMIDES COMPOUND AND PREPARATION METHOD AND USE THEREOF | SHENZHEN EDK PHARMACEUTICAL TECH CO LTD (CN) | 2024-07-17 | — | — | EP | disclosed |
| US-20230382870-A1 | N-AROMATIC AMIDE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | SHENZHEN EDK PHARMACEUTICAL TECH CO LTD (CN) | 2023-11-30 | — | — | US | disclosed |
| US-20230382870-A1 | N-AROMATIC AMIDE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | SHENZHEN EDK PHARMACEUTICAL TECH CO LTD (CN) | 2023-11-30 | — | — | US | disclosed |
| US-20230382870-A1 | N-AROMATIC AMIDE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | SHENZHEN EDK PHARMACEUTICAL TECH CO LTD (CN) | 2023-11-30 | — | — | US | disclosed |
| US-11760727-B2 | N-aromatic amide compounds, preparation methods and uses thereof | SHENZHEN EDK PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2023-09-19 | — | — | US | disclosed |
| US-11760727-B2 | N-aromatic amide compounds, preparation methods and uses thereof | SHENZHEN EDK PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2023-09-19 | — | — | US | disclosed |
| US-11760727-B2 | N-aromatic amide compounds, preparation methods and uses thereof | SHENZHEN EDK PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2023-09-19 | — | — | US | disclosed |
| US-20230115515-A1 | PYRAZOLYLPROPANAMIDE COMPOUNDS AND USES THEREOF FOR TREATMENT OF PROSTATE CANCER | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2023-04-13 | — | — | US | disclosed |
| CN-110963957-B | N-aromatic amide compound and preparation method and application thereof | 深圳恩多凯医药科技有限公司 | 2021-10-22 | — | — | CN | disclosed |
| EP-3858811-A1 | N-AROMATIC AMIDES COMPOUND AND PREPARATION METHOD AND USE THEREOF | Shenzen EDK Pharmaceutical Technology Co., Ltd. (CN) | 2021-08-04 | — | — | EP | disclosed |
| EP-3858811-A1 | N-AROMATIC AMIDES COMPOUND AND PREPARATION METHOD AND USE THEREOF | Shenzen EDK Pharmaceutical Technology Co., Ltd. (CN) | 2021-08-04 | — | — | EP | disclosed |
| US-20210214311-A1 | N-AROMATIC AMIDE COMPUNDS, PREPARATION METHODS AND USES THEREOF | SHENZHEN EDK PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2021-07-15 | — | — | US | disclosed |
| US-20210214311-A1 | N-AROMATIC AMIDE COMPUNDS, PREPARATION METHODS AND USES THEREOF | SHENZHEN EDK PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2021-07-15 | — | — | US | disclosed |
| CN-110963957-A | N-aromatic amide compound and preparation method and application thereof | 深圳恩多凯医药科技有限公司 | 2020-04-07 | — | — | CN | disclosed |
| WO-2020063407-A1 | N-AROMATIC AMIDES COMPOUND AND PREPARATION METHOD AND USE THEREOF | 深圳恩多凯医药科技有限公司 | 2020-04-02 | — | — | WO | disclosed |
| WO-2020063407-A1 | N-AROMATIC AMIDES COMPOUND AND PREPARATION METHOD AND USE THEREOF | 深圳恩多凯医药科技有限公司 | 2020-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382870-A1 | N-AROMATIC AMIDE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | H1-3, H1-0, NAT1 | DYRK1A 3628/4885NR4A2 557/4885MAPK14 4016/4885 |
| US-11760727-B2 | N-aromatic amide compounds, preparation methods and uses thereof | AR, BPHL, CYP19A1 | DYRK1A 3817/4885NR4A2 640/4885MAPK14 3901/4885 |
| US-20210214311-A1 | N-AROMATIC AMIDE COMPUNDS, PREPARATION METHODS AND USES THEREOF | AR, BPHL, CYP19A1 | DYRK1A 3845/4885NR4A2 537/4885MAPK14 3889/4885 |
| US-20230115515-A1 | PYRAZOLYLPROPANAMIDE COMPOUNDS AND USES THEREOF FOR TREATMENT OF PROSTATE CANCER | AR, KLK3, ACP3 | DYRK1A 1957/4885NR4A2 1098/4885MAPK14 3312/4885 |
| US-12358878-B2 | N-aromatic amide compounds, preparation methods and uses thereof | H1-3, H1-0, NAT1 | DYRK1A 3628/4885NR4A2 557/4885MAPK14 4016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.