SCHEMBL11537253

SCHEMBL11537253

Fc1ccc(-c2c[nH]nc2-n2cnnc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 2/20 0.35
LRRK2 Q5S007 2/20 0.35
STK4 Q13043 1/20 0.35
STK3 Q13188 1/20 0.35
NR4A2 P43354 1/20 0.33
GSK3B P49841 2/20 0.33
CLK4 Q9HAZ1 2/20 0.33
CDC7 O00311 1/20 0.33
PIM1 P11309 1/20 0.33
HIPK2 Q9H2X6 1/20 0.33
MAPK14 Q16539 5/20 0.33
GCGR P47871 2/20 0.33
DAPK3 O43293 1/20 0.33
PRKD3 O94806 1/20 0.33
MAP4K4 O95819 1/20 0.33
PAK4 O96013 1/20 0.33
ABL1 P00519 1/20 0.33
NTRK1 P04629 1/20 0.33
LCK P06239 1/20 0.33
CSF1R P07333 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11541771 0.83 ADH5 (0.36) ADH5
SCHEMBL11539457 0.83 ALDH1A1 (0.34) DYRK1ALRRK2STK4STK3GSK3B
SCHEMBL11537638 0.81 LRRK2 (0.40) LRRK2STK4STK3GSK3BCLK4
Hydrochloric Acid SCHEMBL11538599 0.81 LRRK2 (0.33) DYRK1ALRRK2STK4STK3GSK3B
SCHEMBL21891997 0.76 DYRK1A (0.41) DYRK1ALRRK2NR4A2GSK3BCLK4
Nitric Acid SCHEMBL11543671 0.73 TDP1 (0.35) PIM1
SCHEMBL11544141 0.72 LRRK2 (0.40) LRRK2STK4STK3
SCHEMBL11539378 0.72 STK4 (0.41) LRRK2STK4STK3TDO2
SCHEMBL17619924 0.71 MAPK14 (0.49) DYRK1ALRRK2STK4STK3NR4A2
SCHEMBL8360337 0.69 DYRK1A (0.45) DYRK1ALRRK2NR4A2GSK3BCLK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4169838-A PYRAZOLYLTRIAZOLE HERBICIDES AMERICAN CYANAMID COMPANY (US) 1979-10-02 US disclosed
US-4115097-A Pyrazolyltriazole herbicides AMERICAN CYANAMID COMPANY (US) 1978-09-19 US disclosed