Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 10/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18106014 | 0.85 | CYP2C19 (0.62) | CYP2C19ELANEABCB1NPSR1KDM4E | |
| SCHEMBL21892002 | 0.80 | CYP2C19 (0.57) | CYP2C19ELANEABCB1NPSR1MCL1 | |
| SCHEMBL21892018 | 0.79 | ALDH1A1 (0.58) | CYP2C19ELANEKDM4EGAAMAPT | |
| SCHEMBL8925834 | 0.79 | CYP2C19 (1.00) | CYP2C19ELANEABCB1NPSR1KDM4E | |
| SCHEMBL16710294 | 0.79 | CYP2C19 (1.00) | CYP2C19ELANEABCB1NPSR1KDM4E | |
| SCHEMBL28551481 | 0.79 | CYP2C19 (1.00) | CYP2C19ELANEABCB1NPSR1KDM4E | |
| SCHEMBL4237838 | 0.79 | CYP2C19 (1.00) | CYP2C19ELANEABCB1NPSR1KDM4E | |
| SCHEMBL23707006 | 0.71 | MAPT (0.57) | CYP2C19KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL5354624 | 0.71 | CYP2C19 (0.51) | CYP2C19ABCB1KDM4EMAPTKMT2A | |
| SCHEMBL5354631 | 0.71 | CYP2C19 (0.51) | CYP2C19ABCB1KDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10624943-B2 | Kava derived therapeutic compounds and methods of use thereof | Kuality Herbceutics, LLC (US) | 2020-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10624943-B2 | Kava derived therapeutic compounds and methods of use thereof | KLK5, KLK4, KLK2 | CYP2C19 1201/4885ELANE 1672/4885ABCB1 1681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.