Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31352427 | 0.79 | HSD11B1 (0.43) | ALOX5AP | |
| SCHEMBL24655968 | 0.79 | TRPV1 (0.34) | ALOX5APHDAC9GRM5MAPTKDM4E | |
| SCHEMBL29454959 | 0.79 | EPHX2 (0.47) | ALOX5APMAPT | |
| SCHEMBL24656685 | 0.79 | HRH3 (0.34) | HDAC9GRM5HRH3MAPTKDM4E | |
| SCHEMBL29935755 | 0.76 | HDAC9 (0.35) | HDAC9GRM5HRH3MAPTKDM4E | |
| SCHEMBL4556380 | 0.76 | TRIM24 (0.42) | ALOX5APGRM5MAPTLMNAKDM4E | |
| SCHEMBL16202020 | 0.75 | ADORA1 (0.47) | MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL30725595 | 0.75 | ADORA1 (0.47) | MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL21818380 | 0.74 | TP53 (0.40) | HDAC9GRM5MAPTKDM4EMYC | |
| SCHEMBL31381625 | 0.73 | MAPK10 (0.32) | ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020065613-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |