Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24359770 | 0.83 | PDE10A (0.42) | MAPK10MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL2360545 | 0.81 | MEN1 (0.46) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL12830382 | 0.80 | MAPK10 (0.39) | MAPK10PDE10A | |
| SCHEMBL3758184 | 0.80 | NPC1 (0.44) | MAPK10MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL20320623 | 0.80 | KMT2A (0.53) | MAPK10KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL20320622 | 0.79 | BRAF (0.41) | MAPK10RAB9APTGS2 | |
| SCHEMBL18136489 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1RAB9ALMNATSHR | |
| SCHEMBL21849226 | 0.78 | PSEN1 (0.39) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL24655967 | 0.78 | PPARA (0.41) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL3958461 | 0.77 | GPR52 (0.39) | MAPK10MEN1KMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020065613-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |