SCHEMBL21894889

SCHEMBL21894889

C=Cc1ccc(C2(c3c(F)c(F)c(F)c(F)c3F)c3ccccc3-c3ccc(N(c4ccc(-c5ccccc5)cc4)c4ccc(-c5ccc(-c6ccc(N(c7ccc(-c8ccccc8)cc7)c7ccc8c(c7)C(c7ccc(C=C)cc7)(c7c(F)c(F)c(F)c(F)c7F)c7ccccc7-8)cc6)cc5)cc4)cc32)cc1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 3/20 0.33
MEN1 O00255 2/20 0.30
KMT2A Q03164 2/20 0.30
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
OPRK1 P41145 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21895090 0.99 PDK2 (0.32) PDK2
SCHEMBL24994698 0.99 PDK2 (0.32) PDK2
SCHEMBL21894876 0.98 PDK2 (0.32) PDK2MEN1KMT2AKDM4ELMNA
SCHEMBL23790197 0.98 PDK2 (0.32) PDK2MEN1KMT2AKDM4ELMNA
SCHEMBL21895091 0.98 PDK2 (0.32) PDK2MEN1KMT2AKDM4ELMNA
SCHEMBL21894973 0.98 PDK2 (0.32) PDK2MEN1KMT2AKDM4ELMNA
SCHEMBL24614533 0.95 PDK2 (0.36) PDK2
SCHEMBL21895093 0.94 ESR1 (0.31)
SCHEMBL24614512 0.94 PDK2 (0.32) PDK2
SCHEMBL24993779 0.94 PDK2 (0.33) PDK2MEN1KMT2AKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807767-B2 Ink composition for organic light emitting device LG CHEM, LTD. 2023-11-07 US disclosed
US-11807767-B2 Ink composition for organic light emitting device LG CHEM, LTD. 2023-11-07 US disclosed
US-11702550-B2 Coating composition, organic light-emitting diode using same, and method for preparing same LG CHEM, LTD. 2023-07-18 US disclosed
US-11702550-B2 Coating composition, organic light-emitting diode using same, and method for preparing same LG CHEM, LTD. 2023-07-18 US disclosed
US-20230043088-A1 Organic Light Emitting Device LG CHEM, LTD. (KR) 2023-02-09 US disclosed
US-20210277269-A1 Ink Composition for Organic Light Emitting Device LG CHEM, LTD. (KR) 2021-09-09 US disclosed
US-11094887-B2 Fluorene-based compound, organic light-emitting device using same and method for preparing same LG CHEM, LTD. 2021-08-17 US disclosed
EP-3789464-A1 INK COMPOSITION FOR ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2021-03-10 EP disclosed
US-20200277502-A1 Coating Composition, Organic Light-Emitting Diode Using Same, and Method for Preparing Same LG CHEM, LTD. (KR) 2020-09-03 US disclosed
WO-2020067800-A1 INK COMPOSITION FOR ORGANIC LIGHT EMITTING DEVICE 주식회사 엘지화학 2020-04-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11094887-B2 Fluorene-based compound, organic light-emitting device using same and method for preparing same AFF1, LEF1, FMNL1 PDK2 3858/4885MEN1 275/4885KMT2A 1148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.