Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30278737 | 1.00 | USP2 (0.63) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL345968 | 0.85 | USP2 (0.69) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9006395 | 0.85 | USP2 (0.65) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5172119 | 0.85 | USP2 (0.72) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL346937 | 0.85 | USP2 (0.72) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9494373 | 0.85 | USP2 (0.72) | USP2PSEN1PSEN2APH1BNCSTN | |
| Hydrochloric Acid SCHEMBL5171901 | 0.84 | USP2 (0.71) | USP2PSEN1PSEN2APH1BNCSTN | |
| Hydrochloric Acid SCHEMBL5171904 | 0.84 | USP2 (0.71) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8196001 | 0.83 | USP2 (0.73) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL346978 | 0.83 | USP2 (0.69) | USP2PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3896056-A1 | AMINO ACID HAVING FUNCTIONAL GROUP CAPABLE OF INTERMOLECULAR HYDROGEN BONDING, PEPTIDE COMPOUND CONTAINING SAME AND METHOD FOR PRODUCTION THEREOF | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2021-10-20 | — | — | EP | disclosed |
| EP-3636807-A1 | CYCLIC PEPTIDE COMPOUND HAVING HIGH MEMBRANE PERMEABILITY, AND LIBRARY CONTAINING SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 2020-04-15 | — | — | EP | disclosed |