Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | POLA1 | P09884 | 1/20 | 0.61 |
| ▸ | POLD1 | P28340 | 1/20 | 0.61 |
| ▸ | DTYMK | P23919 | 4/20 | 0.61 |
| ▸ | TK1 | P04183 | 3/20 | 0.60 |
| ▸ | TYMS | P04818 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13111576 | 1.00 | POLB (0.66) | POLBPOLA1POLD1DTYMKTK1 | |
| SCHEMBL26033337 | 1.00 | POLB (0.66) | POLBPOLA1POLD1DTYMKTK1 | |
| SCHEMBL19135278 | 1.00 | POLB (0.66) | POLBPOLA1POLD1DTYMKTK1 | |
| SCHEMBL13127048 | 1.00 | POLB (0.66) | POLBPOLA1POLD1DTYMKTK1 | |
| SCHEMBL19663814 | 1.00 | POLB (0.66) | POLBPOLA1POLD1DTYMKTK1 | |
| SCHEMBL19661255 | 1.00 | POLB (0.66) | POLBPOLA1POLD1DTYMKTK1 | |
| SCHEMBL14599412 | 0.94 | POLB (0.71) | POLBPOLA1POLD1DTYMKTK1 | |
| SCHEMBL14138785 | 0.94 | POLB (0.71) | POLBPOLA1POLD1DTYMKTK1 | |
| SCHEMBL22238352 | 0.92 | POLB (0.67) | POLBPOLA1POLD1DTYMKTK1 | |
| SCHEMBL19661248 | 0.92 | POLB (0.67) | POLBPOLA1POLD1DTYMKTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11578094-B2 | Charge-tagged nucleotides and methods of use thereof | ILLUMINA, INC. (US) | 2023-02-14 | — | — | US | disclosed |
| US-20210179657-A1 | CHARGE-TAGGED NUCLEOTIDES AND METHODS OF USE THEREOF | ILLUMINA, INC. (US) | 2021-06-17 | — | — | US | disclosed |
| US-10851131-B2 | Charge-tagged nucleotides and methods of use thereof | ILLUMINA, INC. (US) | 2020-12-01 | — | — | US | disclosed |
| US-20200123193-A1 | CHARGE-TAGGED NUCLEOTIDES AND METHODS OF USE THEREOF | ILLUMINA, INC. (US) | 2020-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210179657-A1 | CHARGE-TAGGED NUCLEOTIDES AND METHODS OF USE THEREOF | POLN, POLRMT, POLM | POLB 6/4885POLA1 12/4885POLD1 46/4885 |
| US-20200123193-A1 | CHARGE-TAGGED NUCLEOTIDES AND METHODS OF USE THEREOF | POLN, POLRMT, POLM | POLB 6/4885POLA1 12/4885POLD1 46/4885 |
| US-10851131-B2 | Charge-tagged nucleotides and methods of use thereof | POLN, POLRMT, POLM | POLB 6/4885POLA1 12/4885POLD1 46/4885 |
| US-11578094-B2 | Charge-tagged nucleotides and methods of use thereof | POLN, POLRMT, POLM | POLB 6/4885POLA1 12/4885POLD1 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.