Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 3/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.30 |
| ▸ | IL6ST | P40189 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10308879 | 1.00 | PIK3CD (0.40) | PIK3CDCNR2PDE1APDE1BPDE1C | |
| SCHEMBL23634006 | 1.00 | PIK3CD (0.40) | PIK3CDCNR2PDE1APDE1BPDE1C | |
| SCHEMBL10308880 | 0.85 | PIK3CD (0.38) | PIK3CDCNR2IL6ST | |
| SCHEMBL20989996 | 0.85 | PIK3CD (0.40) | PIK3CD | |
| SCHEMBL22886416 | 0.83 | PIK3CD (0.39) | PIK3CD | |
| SCHEMBL10308851 | 0.83 | PIK3CD (0.42) | PIK3CDAR | |
| SCHEMBL23634013 | 0.83 | PIK3CD (0.42) | PIK3CDAR | |
| SCHEMBL6639373 | 0.83 | PIK3CD (0.39) | PIK3CDIL6ST | |
| SCHEMBL10308834 | 0.82 | PIK3CD (0.36) | PIK3CDAR | |
| SCHEMBL23634009 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200123132-A1 | ANTIVIRAL COMPOUNDS | GILEAD PHARMASSET LLC | 2020-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200123132-A1 | ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, ZC3HAV1 | PIK3CD 1022/4885CNR2 4830/4885PDE1A 4865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.