Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17070960 | 0.85 | KMT2A (0.49) | KMT2APOLBPADI4FPR2ALDH1A1 | |
| SCHEMBL17068923 | 0.84 | KMT2A (0.50) | KMT2APOLBPADI4FPR2ALDH1A1 | |
| SCHEMBL4408729 | 0.73 | KMT2A (0.51) | KMT2APOLBPADI4FPR2ALDH1A1 | |
| SCHEMBL2434763 | 0.72 | POLB (0.63) | KMT2APOLBPADI4ALDH1A1MEN1 | |
| SCHEMBL11677768 | 0.72 | POLB (0.74) | KMT2APOLBPADI4ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL10756604 | 0.71 | POLB (0.61) | KMT2APOLBPADI4ALDH1A1MEN1 | |
| SCHEMBL9563206 | 0.70 | POLB (0.59) | KMT2APOLBPADI4ALDH1A1LMNA | |
| SCHEMBL11967051 | 0.69 | KMT2A (0.54) | KMT2APOLBPADI4FPR2ALDH1A1 | |
| SCHEMBL8067633 | 0.69 | KMT2A (0.75) | KMT2APOLBPADI4FPR2ALDH1A1 | |
| SCHEMBL24796374 | 0.69 | KMT2A (0.54) | KMT2APOLBPADI4FPR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2880029-B1 | INHIBITORS OF PEPTIDYL ARGININE DEIMINASE (PAD) ENZYMES AND USES THEREOF | HOSPITAL FOR SICK CHILDREN (CA) | 2020-04-22 | — | — | EP | disclosed |