SCHEMBL21898641

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21899805	0.94	AR (0.38)	ARTRPA1ALDH1A1GLAGAA
	SCHEMBL20623796	0.94	AR (0.50)	ARTRPA1ALDH1A1GLAGAA
	SCHEMBL21898542	0.92	AR (0.47)	ARTRPA1ALDH1A1GLAGAA
	SCHEMBL20611855	0.89	AR (0.40)	ARTRPA1ALDH1A1GLAGAA
	SCHEMBL20624306	0.89	AR (0.38)	ARTRPA1ALDH1A1GLAGAA
	SCHEMBL20612237	0.89	AR (0.52)	ARTRPA1PGR
	SCHEMBL21898642	0.89	AR (0.38)	ARTRPA1ALDH1A1GLAGAA
	SCHEMBL20617316	0.88	AR (0.41)	ARTRPA1ALDH1A1GLAGAA
	SCHEMBL22156607	0.88	PDE9A (0.37)	ARTRPA1ALDH1A1GAAHPGD
	SCHEMBL19917813	0.87	AR (0.42)	ARALDH1A1PGRPDK2NR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.