SCHEMBL2189907

SCHEMBL2189907

[C]#CC1c2ccccc2-c2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.41
HTR2A P28223 2/20 0.41
ACHE P22303 3/20 0.38
BCHE P06276 2/20 0.38
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
HDAC9 Q9UKV0 1/20 0.35
HDAC5 Q9UQL6 1/20 0.35
NCOR2 Q9Y618 1/20 0.35
PIM1 P11309 1/20 0.34
POLB P06746 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
CHRM2 P08172 1/20 0.33
HTR1A P08908 1/20 0.33
ADRA2A P08913 1/20 0.33
CHRM1 P11229 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6648437 0.74 PIM1 (0.56) GPR3HTR2AACHEBCHEHDAC3
SCHEMBL68229 0.74 GPR3 (0.41) GPR3HTR2AHDAC3HDAC4HDAC7
SCHEMBL5084440 0.74 GPR3 (0.41) GPR3HTR2AACHEBCHEHDAC3
SCHEMBL2747277 0.74 GPR3 (0.41) GPR3HTR2AACHEBCHEHDAC3
SCHEMBL28049 0.69 GPR3 (0.41) GPR3HTR2AACHEBCHEHDAC3
SCHEMBL29950614 0.67 GPR3 (0.50) GPR3HTR2AACHEBCHEHDAC3
SCHEMBL524603 0.67 GPR3 (0.50) GPR3HTR2AACHEBCHEHDAC3
SCHEMBL8678490 0.67 APP (0.46) GPR3HTR2APOLBCYP1A2CYP2D6
SCHEMBL2001938 0.67 BCHE (0.61) GPR3HTR2AACHEBCHEHDAC3
SCHEMBL1107108 0.65 GPR3 (0.48) GPR3HTR2AACHEBCHEHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10365286-B2 Chromophoric structures for lanthanide chelates RADIOMETER TURKU OY (FI) 2019-07-30 US disclosed
US-10365286-B2 Chromophoric structures for lanthanide chelates RADIOMETER TURKU OY (FI) 2019-07-30 US disclosed
EP-3137573-B1 NEW CHROMOPHORIC STRUCTURES FOR LANTHANIDE CHELATES FIELD OF THE INVENTION RADIOMETER TURKU OY (FI) 2018-08-01 EP disclosed
US-20170089913-A1 NEW CHROMOPHORIC STRUCTURES FOR LANTHANIDE CHELATES RADIOMETER TURKU OY (FI) 2017-03-30 US disclosed
US-20170089913-A1 NEW CHROMOPHORIC STRUCTURES FOR LANTHANIDE CHELATES RADIOMETER TURKU OY (FI) 2017-03-30 US disclosed
EP-3137573-A1 NEW CHROMOPHORIC STRUCTURES FOR LANTHANIDE CHELATES FIELD OF THE INVENTION DHR Finland Oy (FI) 2017-03-08 EP disclosed
EP-3137573-A1 NEW CHROMOPHORIC STRUCTURES FOR LANTHANIDE CHELATES FIELD OF THE INVENTION DHR Finland Oy (FI) 2017-03-08 EP disclosed
WO-2015165826-A1 NEW CHROMOPHORIC STRUCTURES FOR LANTHANIDE CHELATES FIELD OF THE INVENTION DRH FINLAND OY (FI) 2015-11-05 WO disclosed
WO-2015165826-A1 NEW CHROMOPHORIC STRUCTURES FOR LANTHANIDE CHELATES FIELD OF THE INVENTION DRH FINLAND OY (FI) 2015-11-05 WO disclosed
US-8524847-B2 Organic insulating material, varnish for resin film using the same, resin film and semiconductor device SUMITOMO BAKELITE CO., LTD. (JP) 2013-09-03 US disclosed
EP-2157107-B1 ORGANIC INSULATING MATERIAL, VARNISH FOR RESIN FILM USING THE SAME, RESIN FILM AND SEMICONDUCTOR DEVICE SUMITOMO BAKELITE CO (JP) 2013-05-08 EP disclosed
CN-101111499-B Substituted ethynyl gold-nitrogen-containing heterocyclic carbene complex and organic electroluminescent device using the same UBE INDUSTRIES 2012-05-23 CN disclosed
US-20110172351-A1 ORGANIC INSULATING MATERIAL, VARNISH FOR RESIN FILM USING THE SAME, RESIN FILM AND SEMICONDUCTOR DEVICE SUMITOMO BAKELITE CO., LTD. (JP) 2011-07-14 US disclosed
EP-2157107-A1 ORGANIC INSULATING MATERIAL, VARNISH FOR RESIN FILM USING THE SAME, RESIN FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Co., Ltd. (JP) 2010-02-24 EP disclosed
US-20100004379-A1 ORGANIC INSULATING MATERIAL, VARNISH FOR RESIN FILM USING THE SAME, RESIN FILM AND SEMICONDUCTOR DEVICE SUMITOMO BAKELITE CO., LTD. (JP) 2010-01-07 US disclosed
US-20090318610-A1 ORGANIC INSULATING MATERIALS, VARNISHES FOR ORGANIC INSULATING FILM EMPLOYING THEM, ORGANIC INSULATING FILMS AND SEMICONDUCTOR DEVICES SUMITOMO BAKELITE CO., LTD (JP) 2009-12-24 US disclosed
EP-2117009-A1 ORGANIC INSULATING MATERIAL, VARNISH FOR ORGANIC INSULATING FILM USING THE SAME, ORGANIC INSULATING FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Co., Ltd. (JP) 2009-11-11 EP disclosed
CN-101111499-A Substituted ethynyl gold-nitrogenated heterocyclic carbene complex and organic electroluminescent device using same UBE INDUSTRIES (JP) 2008-01-23 CN disclosed