SCHEMBL21899583

SCHEMBL21899583

N[C@@]1(CO)CCc2ccc(Br)cc2C1

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 13/20 0.46
KCNH2 Q12809 3/20 0.46
S1PR5 Q9H228 1/20 0.41
KDM1A O60341 1/20 0.41
PNMT P11086 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7919829 1.00 S1PR1 (0.46) S1PR1KCNH2S1PR5KDM1APNMT
SCHEMBL16605576 0.94 S1PR1 (0.43) S1PR1KCNH2S1PR5KDM1APNMT
SCHEMBL7920039 0.86 PNMT (0.39) S1PR1KCNH2KDM1APNMT
SCHEMBL7918041 0.81 S1PR1 (0.48) S1PR1KCNH2S1PR5
SCHEMBL8558010 0.78 S1PR1 (0.41) S1PR1KCNH2S1PR5
SCHEMBL23976820 0.75 KDM1A (0.41) KDM1APNMT
SCHEMBL29801698 0.75 KDM1A (0.41) KDM1APNMT
SCHEMBL23291576 0.75 KDM1A (0.41) KDM1APNMT
SCHEMBL30060625 0.75 KDM1A (0.41) KDM1APNMT
SCHEMBL23961494 0.75 KDM1A (0.41) KDM1APNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109206383-B Amino alcohol derivatives, pharmaceutical compositions and uses thereof 北京富龙康泰生物技术有限公司 2021-10-19 CN disclosed
EP-3647309-A1 AMINO ALCOHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF Beijing Foreland Pharma Co., Ltd. (CN) 2020-05-06 EP disclosed