SCHEMBL218997

SCHEMBL218997

Cc1cc(I)ccc1N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29439824 0.79
SCHEMBL616552 0.79
SCHEMBL29455233 0.75
SCHEMBL571047 0.75
SCHEMBL78699 0.75
SCHEMBL29674842 0.75
SCHEMBL30179852 0.74
SCHEMBL1639879 0.74
SCHEMBL690777 0.74
SCHEMBL4872121 0.72 ALDH1A1 (0.65)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 462 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116444382-B Synthesis method of 4-iodo-2-methylaniline 浙江司太立制药股份有限公司 2024-09-20 CN claimed
US-11970433-B1 Synthetic route to 2,2′-dimethyl-4,4′-diiodoazobenzene via homo-oxidative cross-coupling of aryl diazonium salt using cu-catalyzed sandmeyer-style reaction King Faisal University (SA) 2024-04-30 US claimed
CN-116444382-A Synthesis method of 4-iodo-2-methylaniline 浙江司太立制药股份有限公司 2023-07-18 CN claimed
CN-113233957-B Preparation method of 2-bromo-5-iodo-benzyl alcohol 成都工业学院 2023-05-02 CN claimed
CN-113233957-A Preparation method of 2-bromo-5-iodo-benzyl alcohol 成都工业学院 2021-08-10 CN claimed
US-8680272-B2 3-arylethynyl substituted quinazolinone compounds COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2014-03-25 US claimed
US-20130317221-A1 3-ARYLETHYNYL SUBSTITUTED QUINAZOLINONE COMPOUNDS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2013-11-28 US claimed
WO-2012111017-A1 3-ARYLETHYNYL SUBSTITUTED QUINAZOLINONE COMPOUNDS CONCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2012-08-23 WO claimed
CN-1358095-A Methods of treating chronic pain using MEK inhibitors WARNER LAMBERT CO (US) 2002-07-10 CN claimed
US-6362369-B1 None US disclosed
EP-4725941-A1 ARYLAMIDE DERIVATIVE HAVING ANTITUMOR ACTIVITY CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2026-04-15 EP disclosed
US-20250114461-A1 CDK2 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2025-04-10 US disclosed
US-12252643-B2 Liquid crystal composition, element and liquid crystal lens or a birefringent lens for stereoscopic image display JNC CORPORATION (JP) 2025-03-18 US disclosed
CN-115803024-B Compositions comprising aryl amide derivatives 中外制药株式会社 2025-01-10 CN disclosed
EP-0287909-A1 Amyloidosis and Alzheimer's disease diagnostic assay and reagents therefor SALUTAR, INC. (US) 1988-10-26 EP disclosed
US-4012222-A Herbicidal compositions containing dioxolane substituted anilids and method therefor VELSICOL CHEMICAL CORPORATION (US) 1977-03-15 US disclosed
US-3948950-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1976-04-06 US disclosed
US-3946045-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1976-03-23 US disclosed
US-3942972-A Dioxolane substituted α-haloanilides as herbicides VELSICOL CHEMICAL CORPORATION (US) 1976-03-09 US disclosed
US-3940259-A Dioxane substituted-α-haloanilides as herbicides VELSICOL CHEMICAL CORPORATION (US) 1976-02-24 US disclosed