Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5460596 | 0.80 | — | — | |
| SCHEMBL6709749 | 0.75 | — | — | |
| SCHEMBL11552377 | 0.67 | SQLE (0.52) | MAPT | |
| SCHEMBL11552375 | 0.67 | SQLE (0.52) | MAPT | |
| SCHEMBL23754414 | 0.65 | LMNA (0.42) | MAPT | |
| SCHEMBL23754413 | 0.65 | LMNA (0.42) | MAPT | |
| SCHEMBL23131744 | 0.64 | — | — | |
| SCHEMBL14103163 | 0.64 | BACE1 (0.41) | — | |
| SCHEMBL8024774 | 0.63 | — | — | |
| SCHEMBL11592900 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020081636-A1 | INDOLE AHR INHIBITORS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2020-04-23 | — | — | WO | disclosed |