Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11077019 | 0.81 | ALDH1A1 (0.42) | AOC3ALDH1A1GAAL3MBTL1ACHE | |
| SCHEMBL19062125 | 0.80 | CPN1 (0.40) | ALDH1A1PBRM1CYP19A1 | |
| SCHEMBL4569063 | 0.79 | GAA (0.40) | AOC3ALDH1A1GAAL3MBTL1ACHE | |
| SCHEMBL20844691 | 0.79 | TACR1 (0.37) | CTSBTACR1IDO1PBRM1 | |
| SCHEMBL18599275 | 0.79 | IDO1 (0.41) | TAAR1IDO1 | |
| Propionitrile SCHEMBL11710236 | 0.79 | AOC3 (0.41) | AOC3ALDH1A1GAAL3MBTL1ACHE | |
| SCHEMBL21848098 | 0.79 | PNP (0.42) | AOC3ALDH1A1ACP3TACR1 | |
| SCHEMBL16079974 | 0.79 | GAA (0.40) | AOC3ALDH1A1GAAL3MBTL1ACHE | |
| SCHEMBL18602502 | 0.78 | AOC3 (0.48) | AOC3ALDH1A1L3MBTL1TAAR1IDO1 | |
| Hydrochloric Acid SCHEMBL17764382 | 0.77 | IDO1 (0.44) | TAAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640242-A1 | ROCK-INHIBITING COMPOUND AND USES THEREOF | Hitgen Ltd. (CN) | 2020-04-22 | — | — | EP | disclosed |