Acetone

Acetone

SCHEMBL2190153

CC(C)=O.NNc1cc(N2C(=O)CCC2=O)ncc1C(=O)O

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.35
GABRP O00591 2/20 0.34
GABRD O14764 2/20 0.34
GABRA1 P14867 2/20 0.34
GABRB1 P18505 2/20 0.34
GABRG2 P18507 2/20 0.34
GABRB3 P28472 2/20 0.34
GABRA5 P31644 2/20 0.34
GABRA3 P34903 2/20 0.34
GABRA2 P47869 2/20 0.34
GABRB2 P47870 2/20 0.34
GABRA4 P48169 2/20 0.34
GABRE P78334 2/20 0.34
GABRA6 Q16445 2/20 0.34
GABRG1 Q8N1C3 2/20 0.34
GABRG3 Q99928 2/20 0.34
GABRQ Q9UN88 2/20 0.34
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetone SCHEMBL17273898 0.99 KDM4E (0.35) KDM4EGABRPGABRDGABRA1GABRB1
SCHEMBL11595020 0.70 KDM4E (0.42) KDM4EGABRPGABRDGABRA1GABRB1
Acetone SCHEMBL4249268 0.67 CA12 (0.36) KDM4EGABRPGABRDGABRA1GABRB1
Acetone SCHEMBL20164099 0.66 CA12 (0.35) KDM4EGABRPGABRDGABRA1GABRB1
Acetone SCHEMBL2032550 0.64 KDM4C (0.54) KDM4ECA12CA1CA9ALDH1A1
SCHEMBL5669489 0.64 KDM4E (0.41) KDM4E
Acetone SCHEMBL5494665 0.64 RECQL (0.54) KDM4EALDH1A1RAB9ARECQLKMT2A
SCHEMBL29133155 0.63 MAPT (0.45) KDM4EALDH1A1GAAPKMTDP1
Acetone SCHEMBL15923153 0.63 KDM4C (0.53) KDM4ECA12CA1CA9ALDH1A1
SCHEMBL3362509 0.63 CA12 (0.37) KDM4ECA12CA1CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2341916-A1 COLOSTRUM COMPOSITION Nanoko A/S (DK) 2011-07-13 EP claimed
EP-2249661-A2 PRODUCTS AND METHODS TO PREVENT INFECTION Multimerics APS (DK) 2010-11-17 EP claimed
WO-2010028652-A1 COLOSTRUM COMPOSITION NANOKO A/S (DK) 2010-03-18 WO claimed
WO-2009092383-A2 PRODUCTS AND METHODS TO PREVENT INFECTION MULTIMERICS APS (DK) 2009-07-30 WO claimed
EP-2885638-B1 MOLECULAR NETS SIENNA CANCER DIAGNOSTICS INC (US) 2020-04-29 EP disclosed
US-9910040-B2 Molecular nets comprising capture agents and linking agents SEVIDENT, INC. (US) 2018-03-06 US disclosed
US-20170261506-A1 Cell Surface Display, Screening and Production of Proteins of Interest CODON DEVICES, INC. 2017-09-14 US disclosed
US-9645146-B2 Cell surface display, screening and production of proteins of interest AGENUS, INC. (US) 2017-05-09 US disclosed
EP-2167119-B1 CHEMICALLY MODIFIED PEPTIDES WITH IMPROVED IMMUNOGENICITY SEC DEP FOR HEALTH (GB) 2016-08-24 EP disclosed
EP-2137308-B1 CELL SURFACE DISPLAY, SCREENING AND PRODUCTION OF PROTEINS OF INTEREST AGENUS INC (US) 2016-08-03 EP disclosed
US-20160074042-A1 NEURAL IMPLANT MEDIZINISCHE HOCHSCHULE HANNOVER (DE) 2016-03-17 US disclosed
US-9259440-B2 Methods for passive immunization MULTIMERICS APS (DK) 2016-02-16 US disclosed
WO-2008152429-A1 CHEMICALLY MODIFIED PEPTIDES WITH IMPROVED IMMUNOGENICITY HEALTH PROTECTION AGENCY (GB) 2008-12-18 WO disclosed
WO-2008118476-A2 CELL SURFACE DISPLAY, SCREENING AND PRODUCTION OF PROTEINS OF INTEREST CODON DEVICES, INC. (US) 2008-10-02 WO disclosed
WO-2008071226-A1 IMPLANT OF CROSS-LINKED SPIDER SILK THREADS MEDIZINISCHE HOCHSCHULE HANNOVER (DE) 2008-06-19 WO disclosed
CN-100371713-C Surface functionalization of gold or silver nanoparticle, and colorimetry detection method for molecule by using the same UNIV SOUTHEAST (CN) 2008-02-27 CN disclosed
CN-1804627-A Surface functionalization of gold or silver nanoparticle, and colorimetry detection method for molecule by using the same UNIV SOUTHEAST (CN) 2006-07-19 CN disclosed
US-20060148124-A1 Nanoparticle conjugates and method of production thereof THE UNIVERSITY OF LIVERPOOL (GB) 2006-07-06 US disclosed
EP-1565216-A1 NANOPARTICLE CONJUGATES AND METHOD OF PRODUCTION THEREOF THE UNIVERSITY OF LIVERPOOL (GB) 2005-08-24 EP disclosed
WO-2004047870-A1 NANOPARTICLE CONJUGATES AND METHOD OF PRODUCTION THEREOF THE UNIVERSITY OF LIVERPOOL (GB) 2004-06-10 WO disclosed