SCHEMBL5669489

SCHEMBL5669489

CC(=O)Cc1cc(NN)c(C(=O)NN2C(=O)CCC2=O)cn1

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15066588 0.72 KDM4E (0.42) KDM4E
Acetone SCHEMBL2190153 0.64 KDM4E (0.35) KDM4E
Acetone SCHEMBL629229 0.64 KDM4E (0.40) KDM4E
SCHEMBL15066590 0.64 KDM4E (0.50) KDM4E
Acetone SCHEMBL17273898 0.64 KDM4E (0.35) KDM4E
Acetone SCHEMBL12813654 0.64 KDM4E (0.39) KDM4E
SCHEMBL1256560 0.62 KDM4E (0.39) KDM4E
SCHEMBL16327606 0.58 L3MBTL1 (0.47) KDM4E
SCHEMBL2264845 0.57 MAPK1 (0.37) KDM4E
SCHEMBL7413307 0.55 BRD4 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060153839-A1 Production of bispecific molecules using polyethylene glycol linkers ELUSYS THERAPEUTICS, INC. (US) 2006-07-13 US disclosed
EP-1539811-A4 PRODUCTION OF BISPECIFIC MOLECULES USING POLYETHYLENE GLYCOL LINKERS ELUSYS THERAPEUTICS INC (US) 2006-05-24 EP disclosed
EP-1539811-A2 PRODUCTION OF BISPECIFIC MOLECULES USING POLYETHYLENE GLYCOL LINKERS Elusys Therapeutics, Inc. (US) 2005-06-15 EP disclosed
WO-2004024889-A2 PRODUCTION OF BISPECIFIC MOLECULES USING POLYETHYLENE GLYCOL LINKERS ELUSYS THERAPEUTICS, INC. (US) 2004-03-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060153839-A1 Production of bispecific molecules using polyethylene glycol linkers TNFSF11, TNFSF10, CLTA KDM4E 3193/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.