Mannitol

Mannitol

SCHEMBL21903100

Nc1nc2ncc([C@H](O)[C@H](O)CO)nc2c(=O)[nH]1.OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.68

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Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.68
NOS1 P29475 9/20 0.46
AKR1B1 P15121 4/20 0.42
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
THRB P10828 1/20 0.39
HPGD P15428 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Xylitol SCHEMBL18285153 0.98 HSD17B10 (0.68) HSD17B10NOS1AKR1B1KDM4EMEN1
SCHEMBL29776903 0.96 HSD17B10 (0.69) HSD17B10NOS1AKR1B1KDM4EMEN1
SCHEMBL4542003 0.96 HSD17B10 (0.69) HSD17B10NOS1AKR1B1KDM4EMEN1
SCHEMBL30287655 0.96 HSD17B10 (0.69) HSD17B10NOS1AKR1B1KDM4EMEN1
SCHEMBL13314521 0.96 HSD17B10 (0.69) HSD17B10NOS1AKR1B1KDM4EMEN1
SCHEMBL29424531 0.96 HSD17B10 (0.69) HSD17B10NOS1AKR1B1KDM4EMEN1
SCHEMBL59519 0.96 HSD17B10 (0.69) HSD17B10NOS1AKR1B1KDM4EMEN1
SCHEMBL59520 0.96 HSD17B10 (0.69) HSD17B10NOS1AKR1B1KDM4EMEN1
Phosphoric Acid SCHEMBL1443736 0.92 HSD17B10 (0.63) HSD17B10NOS1AKR1B1
SCHEMBL12559328 0.86 HSD17B10 (0.66) HSD17B10NOS1AKR1B1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11474067-B2 Detection of serum methionine and glucose by graphite pencil electrode KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2022-10-18 US disclosed
US-20200141891-A1 DETECTION OF SERUM METHIONINE AND GLUCOSE BY GRAPHITE PENCIL ELECTRODE KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2020-05-07 US disclosed