Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 20/20 | 0.70 |
| ▸ | ELOC | Q15369 | 10/20 | 0.54 |
| ▸ | ELOB | Q15370 | 10/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20330399 | 0.96 | VHL (0.64) | VHLELOCELOB | |
| SCHEMBL20329972 | 0.96 | VHL (0.64) | VHLELOCELOB | |
| SCHEMBL20330246 | 0.96 | VHL (0.76) | VHLELOCELOB | |
| SCHEMBL21933144 | 0.93 | VHL (0.70) | VHLELOCELOB | |
| SCHEMBL20330247 | 0.89 | VHL (0.76) | VHLELOCELOB | |
| SCHEMBL24654235 | 0.88 | VHL (0.80) | VHLELOCELOB | |
| SCHEMBL20133017 | 0.88 | VHL (0.64) | VHLELOCELOB | |
| SCHEMBL21673347 | 0.88 | VHL (0.60) | VHLELOCELOB | |
| SCHEMBL20133139 | 0.88 | VHL (0.77) | VHLELOCELOB | |
| SCHEMBL20330400 | 0.88 | VHL (0.61) | VHLELOCELOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10604506-B2 | Modulators of estrogen receptor proteolysis and associated methods of use | ARVINAS OPERATIONS, INC. (US) | 2020-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10604506-B2 | Modulators of estrogen receptor proteolysis and associated methods of use | ADRM1, MDM2, ESR2 | VHL 6/4885ELOC 1550/4885ELOB 834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.