Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | DAO | P14920 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | FLT3 | P36888 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31154492 | 0.84 | FLT3 (0.62) | KDM4EMAPTDAOHPGDSRD5A2 | |
| SCHEMBL23902685 | 0.84 | FLT3 (0.62) | KDM4EMAPTDAOHPGDSRD5A2 | |
| SCHEMBL3445907 | 0.83 | KDM4E (0.55) | KDM4EMAPTDAOHPGDSRD5A2 | |
| SCHEMBL31255783 | 0.83 | FLT3 (0.61) | KDM4EMAPTDAOHPGDSRD5A2 | |
| SCHEMBL3976369 | 0.81 | KDM4E (0.72) | KDM4EMAPTDAOHPGDSRD5A2 | |
| SCHEMBL30381896 | 0.81 | KDM4E (0.72) | KDM4EMAPTDAOHPGDSRD5A2 | |
| SCHEMBL7890207 | 0.81 | KDM4E (0.72) | KDM4EMAPTDAOHPGDSRD5A2 | |
| SCHEMBL7890214 | 0.81 | KDM4E (0.72) | KDM4EMAPTDAOHPGDSRD5A2 | |
| Indole-2-Carboxylic Acid SCHEMBL29395165 | 0.81 | KDM4E (1.00) | KDM4EMAPTDAOHPGDSRD5A2 | |
| Indole-2-Carboxylic Acid SCHEMBL1935 | 0.81 | KDM4E (1.00) | KDM4EMAPTDAOHPGDSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212450-A2 | METHOD FOR INCREASING THE YIELD OF RECOMBINANT PROTEINS IN MICROBIAL FERMENTATION PROCESSES | Pharmacia AB (SE) | 2002-06-12 | — | — | EP | claimed |
| WO-2001020016-A2 | METHOD FOR INCREASING THE YIELD OF RECOMBINANT PROTEINS IN MICROBIAL FERMENTATION PROCESSES | PHARMACIA AB (SE) | 2001-03-22 | — | — | WO | claimed |
| CN-120138046-A | Compositions and methods for treating alpha 1-antitrypsin deficiency | 比姆医疗股份有限公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-120005859-A | Compositions and methods for treating heme lesions | 比姆医疗股份有限公司 | 2025-05-16 | — | — | CN | disclosed |
| CN-114096666-B | Compositions and methods for treating heme lesions | 比姆医疗股份有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-114072180-B | Compositions and methods for treating alpha 1-antitrypsin deficiency | 比姆医疗股份有限公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-116497067-B | Compositions and methods for treating heme lesions | 比姆医疗股份有限公司 | 2025-01-24 | — | — | CN | disclosed |
| US-20240117384-A1 | METHOD FOR CONVERTING NUCLEIC ACID SEQUENCE OF CELL SPECIFICALLY CONVERTING NUCLEIC ACID BASE OF TARGETED DNA USING CELL ENDOGENOUS DNA MODIFYING ENZYME, AND MOLECULAR COMPLEX USED THEREIN | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2024-04-11 | — | — | US | disclosed |
| CN-116854830-A | Starch-indoloic acid derivatives and their use | 山东善维免疫科技有限公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-116497067-A | Compositions and methods for treating heme lesions | 比姆医疗股份有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-113912743-B | Starch-indoloic acid derivative and preparation method and application thereof | 山东善维免疫科技有限公司 | 2023-07-18 | — | — | CN | disclosed |
| US-4675183-A | AMINO ACID SOLUBILIZER | Kwoya Hakko Kogyo Co., Ltd. (JP) | 1987-06-23 | — | — | US | disclosed |
| EP-0201882-A2 | Fish prolactin polypeptide and derivatives thereof | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1986-11-20 | — | — | EP | disclosed |
| EP-0170917-A1 | Novel human interferon-gamma polypeptide derivative | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1986-02-12 | — | — | EP | disclosed |
| EP-0163111-A2 | Method for solubilization of interferon | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1985-12-04 | — | — | EP | disclosed |
| EP-0158198-A1 | DNA and use thereof | Takeda Chemical Industries, Ltd. (JP) | 1985-10-16 | — | — | EP | disclosed |
| EP-0102634-A1 | Recombinant DNA, microorganism transformed therewith and use thereof | Takeda Chemical Industries, Ltd. (JP) | 1984-03-14 | — | — | EP | disclosed |
| EP-0089676-A2 | Novel DNA and use thereof | Takeda Chemical Industries, Ltd. (JP) | 1983-09-28 | — | — | EP | disclosed |
| US-4356324-A | CHIRAL LIGANDS FOR RHODIUM HYDROGENATION CATALYSTS | DEGUSSA AKTIENGESELLSCHAFT, A GERMAN CORP. (DE) | 1982-10-26 | — | — | US | disclosed |
| EP-0020251-A2 | DNA transfer vector, host transformed with it, vaccine, and their production | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1980-12-10 | — | — | EP | disclosed |