Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 19/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22203537 | 0.80 | GLS (1.00) | GLS | |
| SCHEMBL17412290 | 0.80 | GLS (1.00) | GLS | |
| SCHEMBL17419859 | 0.71 | GLS (0.74) | GLS | |
| SCHEMBL17411686 | 0.69 | GLS (1.00) | GLS | |
| SCHEMBL17412104 | 0.69 | GLS (0.73) | GLS | |
| SCHEMBL29753356 | 0.69 | GLS (0.73) | GLS | |
| SCHEMBL21907606 | 0.69 | GLS (0.66) | GLS | |
| SCHEMBL21325806 | 0.69 | GLS (0.68) | GLS | |
| SCHEMBL17419827 | 0.69 | GLS (0.70) | GLS | |
| SCHEMBL29752884 | 0.69 | GLS (0.70) | GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3164394-B1 | GLS1 INHIBITORS FOR TREATING DISEASES | UNIV TEXAS (US) | 2020-04-01 | — | — | EP | disclosed |