Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24915032 | 0.67 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL11751761 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL9216558 | 0.62 | CYP1A2 (0.38) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL13460714 | 0.61 | CYP1A2 (0.37) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5153957 | 0.60 | TSHR (0.58) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL21887121 | 0.60 | KDM4E (0.62) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL2221926 | 0.60 | MAPT (0.38) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7324209 | 0.60 | TDP1 (0.62) | MEN1CYP3A4KMT2A | |
| SCHEMBL23342470 | 0.59 | KDM4E (0.30) | — | |
| SCHEMBL22836423 | 0.59 | MAPT (0.57) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3164394-B1 | GLS1 INHIBITORS FOR TREATING DISEASES | UNIV TEXAS (US) | 2020-04-01 | — | — | EP | disclosed |