SCHEMBL2190885

SCHEMBL2190885

CCCCCCCCC=CC(=O)N[C@@H](C)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 0.62
SMN1; SMN2 Q16637 1/20 0.58
SLC6A5 Q9Y345 1/20 0.58
CNR1 P21554 1/20 0.49
CNR2 P34972 1/20 0.49
PPARG P37231 2/20 0.47
PPARA Q07869 2/20 0.47
PSMB11 A5LHX3 1/20 0.47
PSMA7 O14818 1/20 0.47
PSMB1 P20618 1/20 0.47
PSMA1 P25786 1/20 0.47
PSMA2 P25787 1/20 0.47
PSMA3 P25788 1/20 0.47
PSMA4 P25789 1/20 0.47
PSMB8 P28062 1/20 0.47
PSMB9 P28065 1/20 0.47
PSMA5 P28066 1/20 0.47
PSMB4 P28070 1/20 0.47
PSMB6 P28072 1/20 0.47
PSMB5 P28074 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10956216 1.00 FAAH (0.62) FAAHSMN1; SMN2SLC6A5CNR1CNR2
SCHEMBL10951078 1.00 FAAH (0.62) FAAHSMN1; SMN2SLC6A5CNR1CNR2
SCHEMBL1956847 0.89 FAAH (0.74) FAAHSMN1; SMN2SLC6A5CNR2BLM
SCHEMBL9650046 0.88 FAAH (0.68) FAAHSMN1; SMN2SLC6A5CNR1CNR2
SCHEMBL9649967 0.88 FAAH (0.68) FAAHSMN1; SMN2SLC6A5CNR1CNR2
SCHEMBL9650039 0.88 FAAH (0.68) FAAHSMN1; SMN2SLC6A5CNR1CNR2
SCHEMBL31026959 0.88 FAAH (0.68) FAAHSMN1; SMN2SLC6A5CNR1CNR2
SCHEMBL9649958 0.88 FAAH (0.68) FAAHSMN1; SMN2SLC6A5CNR1CNR2
SCHEMBL14972500 0.88 FAAH (0.68) FAAHSMN1; SMN2SLC6A5CNR1CNR2
SCHEMBL8036368 0.85 CNR1 (0.53) FAAHCNR1CNR2PSMB11PSMA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2341891-B1 N-UNDECYLENOYL PHENYLALANINE MONOESTER POLYOL, METHOD OF PREPARATION, AND USE THEREOF AS A SKIN LIGHTENING AGENT SEPPIC SA (FR) 2014-06-18 EP disclosed
US-8323627-B2 Monoester of N-undecylenoyl phenylalanine and polyol, method for preparing same, and use of said esters as a skin lightening agent SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2012-12-04 US disclosed
US-20110171150-A1 MONOESTER OF N-UNDECYLENOYL PHENYLALANINE AND POLYOL, METHOD FOR PREPARING SAME, AND USE OF SAID ESTERS AS A SKIN LIGHTENING AGENT SOCIETE DEXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMQUES SEPPIC (FR) 2011-07-14 US disclosed
EP-2341891-A2 MONOESTER OF N-UNDECYLENOYL PHENYLALANINE AND POLYOL, METHOD FOR PREPARING SAME, AND USE OF SAID ESTERS AS A SKIN LIGHTENING AGENT Societe D'Exploitation De Produits Pour Les Industries Chimiques Seppic (FR) 2011-07-13 EP disclosed
WO-2010034917-A2 MONOESTER OF N-UNDECYLENOYL PHENYLALANINE AND POLYOL, METHOD FOR PREPARING SAME, AND USE OF SAID ESTERS AS A SKIN LIGHTENING AGENT SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2010-04-01 WO disclosed
EP-0983055-B1 COMPOSITION COMPRISING AN AMINO ACID N-UNDECYLENOYL; APPLICATION IN COSMETICS SEPPIC SA (FR) 2004-04-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110171150-A1 MONOESTER OF N-UNDECYLENOYL PHENYLALANINE AND POLYOL, METHOD FOR PREPARING SAME, AND USE OF SAID ESTERS AS A SKIN LIGHTENING AGENT NOTUM, PAH, TYR FAAH 462/4885SMN1; SMN2 3276/4885SLC6A5 4177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.