Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CPB1 | P15086 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | TLR4 | O00206 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1006562 | 0.86 | ALDH1A1 (0.65) | ALDH1A1GAATSHRCPB1EPHX1 | |
| SCHEMBL30736153 | 0.85 | ALDH1A1 (0.56) | ALDH1A1GAATSHRCPB1EPHX1 | |
| SCHEMBL25674801 | 0.85 | ALDH1A1 (0.58) | ALDH1A1GAATSHRCPB1EPHX1 | |
| Hydrochloric Acid SCHEMBL25328114 | 0.84 | ALDH1A1 (0.63) | ALDH1A1GAATSHRCPB1EPHX1 | |
| SCHEMBL26986433 | 0.84 | ALDH1A1 (0.67) | ALDH1A1GAATSHRCPB1EPHX1 | |
| SCHEMBL30398163 | 0.82 | ALDH1A1 (0.45) | ALDH1A1GAATSHRCPB1EPHX1 | |
| SCHEMBL22042447 | 0.81 | ALDH1A1 (0.64) | ALDH1A1GAATSHRCPB1EPHX1 | |
| SCHEMBL21811433 | 0.81 | ALDH1A1 (0.54) | ALDH1A1GAATSHRCPB1EPHX1 | |
| SCHEMBL10449418 | 0.81 | ALDH1A1 (0.59) | ALDH1A1GAATSHRCPB1EPHX1 | |
| SCHEMBL10321293 | 0.81 | ALDH1A1 (0.59) | ALDH1A1GAATSHRCPB1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020056089-A1 | PHENOXY-PYRIDYL-PYRIMIDINE COMPOUNDS AND METHODS OF USE | GENENTECH, INC. (US) | 2020-03-19 | — | — | WO | disclosed |