Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KDM4A | O75164 | 4/20 | 0.55 |
| ▸ | KDM4B | O94953 | 4/20 | 0.55 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.55 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.53 |
| ▸ | KDM5C | P41229 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21376526 | 0.91 | ADORA3 (0.74) | ADORA3ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL21909785 | 0.89 | ADORA3 (0.67) | ADORA3ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL29978117 | 0.84 | ADORA3 (0.66) | ADORA3ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL664484 | 0.84 | ADORA3 (0.66) | ADORA3ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL21376614 | 0.84 | ADORA3 (0.63) | ADORA3ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL21376813 | 0.84 | GRM1 (0.71) | ADORA3ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL21376816 | 0.84 | ADORA3 (0.71) | ADORA3ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL21376527 | 0.83 | ADORA3 (0.67) | ADORA3ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL21376823 | 0.82 | ADORA3 (0.58) | ADORA3ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL21376529 | 0.82 | ADORA3 (0.58) | ADORA3ALDH1A1MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626240-A1 | PROCESS OF PREPARATION OF A N-ARYL BENZYL SULFONAMIDE SUBSTITUTED WITH AN AMIDO GROUP | StemSynergy Therapeutics, Inc. (US) | 2020-03-25 | — | — | EP | disclosed |