SCHEMBL21914812

SCHEMBL21914812

C[Si](C)(C)CCOCn1nc(C(F)F)nc1-c1ccc(O)cc1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 2/20 0.35
DGAT1 O75907 10/20 0.35
F2RL1 P55085 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21889223 0.82 DGAT1 (0.46) AOC3DGAT1
SCHEMBL16661224 0.81 DGAT1 (0.42) DGAT1
SCHEMBL21889307 0.79 AOC3 (0.39) AOC3DGAT1
SCHEMBL21889839 0.78 AOC3 (0.45) AOC3DGAT1
SCHEMBL21889200 0.77 AOC3 (0.37) AOC3DGAT1
SCHEMBL21914360 0.77 NPC1 (0.38) DGAT1
SCHEMBL21889523 0.76 DGAT1 (0.35) AOC3DGAT1
SCHEMBL21889556 0.76 DGAT1 (0.33) DGAT1
SCHEMBL21889297 0.75 DGAT1 (0.36) AOC3DGAT1
SCHEMBL21914802 0.75 DGAT1 (0.36) AOC3DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3626699-B1 SSAO INHIBITOR SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) 2023-07-12 EP disclosed
EP-3626699-A1 SSAO INHIBITOR Shandong Danhong Pharmaceutical Co., Ltd. (CN) 2020-03-25 EP disclosed